OPKO Health, Inc.

EDGAR

Annual consolidated revenue for 2025: about USD 606.9M, using the latest reported figures. The previous period, 2024, was about USD 713.1M.

Watchlist

Latest quarter

Revenue

164 million USD

2026 Q2 · USD

Exact inputs and evidence

Operating margin

-4.26%

2026 Q2 · %

Exact inputs and evidence
  • Operating Income: -6972000 USD Source
  • Revenue: 163580000 USD Source

Operating cash flow

-43.5 million USD

2026 Q2 · USD

Exact inputs and evidence
  • Operating Cash Flow: -62810000 USD Source
  • Operating Cash Flow: -19310000 USD Source
Cash and cash equivalents
301 million USD Source
Exact value

300761000 USD

Long-term debt including current maturities
349 million USD Source
Exact value

349050000 USD

Shares outstanding
Not available

Trailing twelve months

The four most recent complete quarters added together. This gives a full-year view that includes the latest quarterly results.

Revenue

588 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Revenue: 151669000 USD · 2025-07-01 – 2025-09-30 Source
  • Revenue: 148451000 USD · 2025-10-01 – 2025-12-31 Source
  • Revenue: 124196000 USD · 2026-01-01 – 2026-03-31 Source
  • Revenue: 163580000 USD · 2026-04-01 – 2026-06-30 Source

Net income

-72.9 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Net income: 21631000 USD · 2025-07-01 – 2025-09-30 Source
  • Net income: -31257000 USD · 2025-10-01 – 2025-12-31 Source
  • Net income: -54848000 USD · 2026-01-01 – 2026-03-31 Source
  • Net income: -8416000 USD · 2026-04-01 – 2026-06-30 Source

Operating cash flow

-123 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Operating cash flow: -152621000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: -117974000 USD · 2025-01-01 – 2025-06-30 Source
  • Operating cash flow: -178542000 USD · 2025-01-01 – 2025-12-31 Source
  • Operating cash flow: -152621000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: -19310000 USD · 2026-01-01 – 2026-03-31 Source
  • Operating cash flow: -62810000 USD · 2026-01-01 – 2026-06-30 Source
  • Operating cash flow: -19310000 USD · 2026-01-01 – 2026-03-31 Source

Company performance

Up to ten complete financial years · consolidated figures

Includes later revisions to earlier periods. Annual charts exclude incomplete years.

Latest filing recorded: 2026-10-15.

Financial data available through: 2025-12-31.

Coverage by financial measure
  • Revenue: 11 of 11 periods available· newest 2025-12-31
  • Operating income: 11 of 11 periods available· newest 2025-12-31
  • Net income: 11 of 11 periods available· newest 2025-12-31
  • Operating cash flow: 11 of 11 periods available· newest 2025-12-31
  • capital expenditure: No compatible figures in this window
  • Total assets: 11 of 11 periods available· newest 2025-12-31
  • Total liabilities: 11 of 11 periods available· newest 2025-12-31
  • Current assets: 11 of 11 periods available· newest 2025-12-31
  • Current liabilities: 11 of 11 periods available· newest 2025-12-31
  • Cash and cash equivalents: 11 of 11 periods available· newest 2025-12-31
  • Long-term debt including current maturities: 7 of 11 periods available· newest 2025-12-31
  • shares outstanding: No compatible figures in this window

Coverage describes values retained in this snapshot. Missing values are not zero; loading limits are reported separately.

What changed year over year

Latest complete year compared with the corresponding period one year earlier. These are measured changes; they do not establish their business causes.

  • Revenue

    -14.9%

    Prior period

    USD 713.14 million

    –

    Current period

    USD 606.88 million

    –

    Exact inputs and evidence

    606879000 − 713142000 = -106263000 USD

    713142000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    606879000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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  • Net income

    −USD 172.46 million

    Prior period

    −USD 53.22 million

    –

    Current period

    −USD 225.68 million

    –

    Exact inputs and evidence

    -225680000 − -53224000 = -172456000 USD

    -53224000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    -225680000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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  • Operating cash flow

    +USD 4.95 million

    Prior period

    −USD 183.49 million

    –

    Current period

    −USD 178.54 million

    –

    Exact inputs and evidence

    -178542000 − -183489000 = 4947000 USD

    -183489000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    -178542000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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Comparable inputs unavailable for: Capital expenditure.

Where revenue goes

How a period’s revenue divides into costs and what remains as profit. Items marked Derived are calculated by subtraction from reported figures.

2025 2025-01-01 – 2025-12-31

  • Revenue USD 606.88 million 100% of revenue
  • Operating costs Derived USD 724.29 million 119% of revenue
  • Operating income −USD 117.41 million −19% of revenue
  • Tax, interest and other Derived USD 108.27 million 18% of revenue
  • Net income −USD 225.68 million −37% of revenue

Cash

  • Operating cash flow −USD 178.54 million −29% of revenue
  • Capital expenditure Unavailable An input is unavailable.
  • Free cash flow Derived Unavailable An input is unavailable.

Share of revenue by period

  • Net income
  • Tax, interest and other
  • Operating costs
  • 2016 Operating loss: operating costs were 109% of revenue.
  • 2017 Operating loss: operating costs were 129% of revenue.
  • 2018 Operating loss: operating costs were 117% of revenue.
  • 2019 Operating loss: operating costs were 130% of revenue.
  • 2020 96%
  • 2021 Net loss: net income was −1.7% of revenue.
  • 2022 Operating loss: operating costs were 123% of revenue.
  • 2023 Operating loss: operating costs were 118% of revenue.
  • 2024 Operating loss: operating costs were 121% of revenue.
  • 2025 Operating loss: operating costs were 119% of revenue.
Values and sources
Revenue breakdown by annual reporting period
PeriodRevenueOperating costsOperating incomeTax, interest and otherNet incomeFree cash flowSource
2016 2016-01-01 – 2016-12-311117494000 1214045000 Derived -96551000 -48192000 Derived -48359000 Unavailable
Source
2017 2017-01-01 – 2017-12-31966006000 1242448000 Derived -276442000 28808000 Derived -305250000 Unavailable
Source
2018 2018-01-01 – 2018-12-31990266000 1161463000 Derived -171197000 -18157000 Derived -153040000 Unavailable
Source
2019 2019-01-01 – 2019-12-31901935000 1175987000 Derived -274052000 40873000 Derived -314925000 Unavailable
Source
2020 2020-01-01 – 2020-12-311435413000 1377699000 Derived 57714000 27128000 Derived 30586000 Unavailable
Source
2021 2021-01-01 – 2021-12-311774718000 1755968000 Derived 18750000 48893000 Derived -30143000 Unavailable
Source
2022 2022-01-01 – 2022-12-311004196000 1230449000 Derived -226253000 102152000 Derived -328405000 Unavailable
Source
2023 2023-01-01 – 2023-12-31863495000 1020516000 Derived -157021000 31842000 Derived -188863000 Unavailable
Source
2024 2024-01-01 – 2024-12-31713142000 865207000 Derived -152065000 -98841000 Derived -53224000 Unavailable
Source
2025 2025-01-01 – 2025-12-31606879000 724288000 Derived -117409000 108271000 Derived -225680000 Unavailable
Source

Amounts are exact, in USD.

Growth

Sales over time and how quickly they are changing.

Revenue

Revenue reported for each complete financial period.

USD 606.9M 2025
Revenue historyRevenue reported for each complete financial period. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.1.9B1.4B958.3M479.2M0.0201620212025
Values and sources
Revenue values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Revenue1117494000
2017Revenue966006000
2018Revenue990266000
2019Revenue901935000
2020Revenue1435413000
2021Revenue1774718000
2022Revenue1004196000
2023Revenue863495000
2024Revenue713142000
2025Revenue606879000

Revenue growth

Change in revenue from the same financial period one year earlier.

-14.9% 2025
Revenue growth historyChange in revenue from the same financial period one year earlier. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.165%109%53%-3%-59%201620212025
Values and sources
Revenue growth values and source evidence
PeriodSeriesValueSource evidence
2016Year over year149.7%
2017Year over year-13.6%
2018Year over year2.5%
2019Year over year-8.9%
2020Year over year59.1%
2021Year over year23.6%
2022Year over year-43.4%
2023Year over year-14%
2024Year over year-17.4%
2025Year over year-14.9%

Profit and cash

How much revenue becomes profit, and how much cash operations generate.

Profit margins

Operating income, net income and free cash flow as a share of revenue.

Operating margin -19.3% 2025
Net margin -37.2% 2025
Profit margins historyOperating income, net income and free cash flow as a share of revenue. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.7%-5%-17%-29%-40%201620212025
  • Operating margin
  • Net margin
  • Free cash flow margin
Values and sources
Profit margins values and source evidence
PeriodSeriesValueSource evidence
2016Operating margin-8.6%
2017Operating margin-28.6%
2018Operating margin-17.3%
2019Operating margin-30.4%
2020Operating margin4%
2021Operating margin1.1%
2022Operating margin-22.5%
2023Operating margin-18.2%
2024Operating margin-21.3%
2025Operating margin-19.3%
2016Net margin-4.3%
2017Net margin-31.6%
2018Net margin-15.5%
2019Net margin-34.9%
2020Net margin2.1%
2021Net margin-1.7%
2022Net margin-32.7%
2023Net margin-21.9%
2024Net margin-7.5%
2025Net margin-37.2%
2016Free cash flow marginNot reported
2017Free cash flow marginNot reported
2018Free cash flow marginNot reported
2019Free cash flow marginNot reported
2020Free cash flow marginNot reported
2021Free cash flow marginNot reported
2022Free cash flow marginNot reported
2023Free cash flow marginNot reported
2024Free cash flow marginNot reported
2025Free cash flow marginNot reported

Operating cash flow

Cash generated by the company’s normal business operations.

USD -178.5M 2025
Operating cash flow historyCash generated by the company’s normal business operations. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.57.3M-7.3M-72.0M-136.7M-201.3M201620212025
Values and sources
Operating cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Operating cash flow32046000
2017Operating cash flow-92080000
2018Operating cash flow-109141000
2019Operating cash flow-172522000
2020Operating cash flow39476000
2021Operating cash flow38337000
2022Operating cash flow-95189000
2023Operating cash flow-28197000
2024Operating cash flow-183489000
2025Operating cash flow-178542000

Free cash flow

Operating cash flow minus capital expenditure for the same period and unit.

Not enough comparable data to show this history.
Values and sources
Free cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Free cash flowUnavailable
2017Free cash flowUnavailable
2018Free cash flowUnavailable
2019Free cash flowUnavailable
2020Free cash flowUnavailable
2021Free cash flowUnavailable
2022Free cash flowUnavailable
2023Free cash flowUnavailable
2024Free cash flowUnavailable
2025Free cash flowUnavailable

Balance sheet

Liabilities and short-term ability to meet obligations at each period end.

Liabilities to assets

Total liabilities as a share of total assets.

34.4% 2025
Liabilities to assets historyTotal liabilities as a share of total assets. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.41%31%20%10%0%201620212025
Values and sources
Liabilities to assets values and source evidence
PeriodSeriesValueSource evidence
2016Liabilities / assets26%
2017Liabilities / assets28.8%
2018Liabilities / assets26.9%
2019Liabilities / assets30.1%
2020Liabilities / assets32.4%
2021Liabilities / assets29.8%
2022Liabilities / assets27.9%
2023Liabilities / assets30.9%
2024Liabilities / assets37.9%
2025Liabilities / assets34.4%

Current assets to current liabilities

Current assets divided by current liabilities.

3.97× 2025
Current assets to current liabilities historyCurrent assets divided by current liabilities. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.4.28×3.21×2.14×1.07×0.00×201620212025
Values and sources
Current assets to current liabilities values and source evidence
PeriodSeriesValueSource evidence
2016Current assets / current liabilities2.01×
2017Current assets / current liabilities1.12×
2018Current assets / current liabilities1.1×
2019Current assets / current liabilities1.3×
2020Current assets / current liabilities1.39×
2021Current assets / current liabilities2.49×
2022Current assets / current liabilities1.85×
2023Current assets / current liabilities1.55×
2024Current assets / current liabilities3.43×
2025Current assets / current liabilities3.97×

Cash generation

Compare reported profit with operating cash and capital spending. Free cash flow is calculated as operating cash flow minus capital expenditure when both exact, consolidated amounts match the same period and unit.

Cash generation by annual reporting period
PeriodNet incomeOperating cash flowCapital expenditureFree cash flow
2016 2016-01-01 – 2016-12-31
−USD 48.36 million
Exact value

Exact value: -48359000 USD

2016-01-01 – 2016-12-31: -48359000 USD Inspect Net Income Open source
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USD 32.05 million
Exact value

Exact value: 32046000 USD

2016-01-01 – 2016-12-31: 32046000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2017 2017-01-01 – 2017-12-31
−USD 305.25 million
Exact value

Exact value: -305250000 USD

2017-01-01 – 2017-12-31: -305250000 USD Inspect Net Income Open source
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−USD 92.08 million
Exact value

Exact value: -92080000 USD

2017-01-01 – 2017-12-31: -92080000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2018 2018-01-01 – 2018-12-31
−USD 153.04 million
Exact value

Exact value: -153040000 USD

2018-01-01 – 2018-12-31: -153040000 USD Inspect Net Income Open source
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−USD 109.14 million
Exact value

Exact value: -109141000 USD

2018-01-01 – 2018-12-31: -109141000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2019 2019-01-01 – 2019-12-31
−USD 314.93 million
Exact value

Exact value: -314925000 USD

2019-01-01 – 2019-12-31: -314925000 USD Inspect Net Income Open source
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−USD 172.52 million
Exact value

Exact value: -172522000 USD

2019-01-01 – 2019-12-31: -172522000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2020 2020-01-01 – 2020-12-31
USD 30.59 million
Exact value

Exact value: 30586000 USD

2020-01-01 – 2020-12-31: 30586000 USD Inspect Net Income Open source
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USD 39.48 million
Exact value

Exact value: 39476000 USD

2020-01-01 – 2020-12-31: 39476000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2021 2021-01-01 – 2021-12-31
−USD 30.14 million
Exact value

Exact value: -30143000 USD

2021-01-01 – 2021-12-31: -30143000 USD Inspect Net Income Open source
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USD 38.34 million
Exact value

Exact value: 38337000 USD

2021-01-01 – 2021-12-31: 38337000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2022 2022-01-01 – 2022-12-31
−USD 328.41 million
Exact value

Exact value: -328405000 USD

2022-01-01 – 2022-12-31: -328405000 USD Inspect Net Income Open source
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−USD 95.19 million
Exact value

Exact value: -95189000 USD

2022-01-01 – 2022-12-31: -95189000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2023 2023-01-01 – 2023-12-31
−USD 188.86 million
Exact value

Exact value: -188863000 USD

2023-01-01 – 2023-12-31: -188863000 USD Inspect Net Income Open source
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−USD 28.2 million
Exact value

Exact value: -28197000 USD

2023-01-01 – 2023-12-31: -28197000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2024 2024-01-01 – 2024-12-31
−USD 53.22 million
Exact value

Exact value: -53224000 USD

2024-01-01 – 2024-12-31: -53224000 USD Inspect Net Income Open source
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−USD 183.49 million
Exact value

Exact value: -183489000 USD

2024-01-01 – 2024-12-31: -183489000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2025 2025-01-01 – 2025-12-31
−USD 225.68 million
Exact value

Exact value: -225680000 USD

2025-01-01 – 2025-12-31: -225680000 USD Inspect Net Income Open source
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−USD 178.54 million
Exact value

Exact value: -178542000 USD

2025-01-01 – 2025-12-31: -178542000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

Capital expenditure uses the canonical mapped positive-spending convention. A missing, ambiguous, incompatible, or negative-sign input is left blank. Values use the latest reported version.

Dataset coverage and company identifiers

Coverage reflects filings processed into this Fundies dataset; it does not imply every source filing is loaded.

210 filings · 7,504 latest values · 7,504 originally reported values

Dataset published . Source filing dates and reporting periods are shown separately.

Identifiers: 0000944809, 944809, OPK, edgar:944809

Also known as CYTOCLONAL PHARMACEUTICS INC /DE, EXEGENICS INC, OPKO HEALTH, INC., OPKO Health, Inc., Opko Health, Inc., eXegenics Inc