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SCIENCE 37 HOLDINGS, INC.

EDGAR

LSAQ Quarterly report (10-Q) · filed 2023-11-07

19 filing records in this dataset, filed from 2020-10-14 to 2023-11-07. Reported financial figures are available; chart coverage varies by period.

Inspect reported changes Compare with another company Historical disclosures Search filings Segments

Watchlist

Latest quarter

Revenue

14.9 million USD

2023 Q3 · USD

Exact inputs and evidence

Revenue: 14887000 USD Source

Operating margin

-97.7%

2023 Q3 · %

Exact inputs and evidence

Operating Income: -14544000 USD Source
Revenue: 14887000 USD Source

Operating cash flow

-400 thousand USD

2023 Q3 · USD

Exact inputs and evidence

Operating Cash Flow: -33125000 USD Source
Operating Cash Flow: -32725000 USD Source

Free cash flow

-404 thousand USD

2023 Q3 · USD

Exact inputs and evidence

Operating Cash Flow: -33125000 USD Source
Operating Cash Flow: -32725000 USD Source
Capital Expenditure: 31000 USD Source
Capital Expenditure: 27000 USD Source

Cash and cash equivalents: 56.4 million USD 2023-09-30 Source
Exact value

56407000 USD
Long-term debt including current maturities: Not available
Shares outstanding: 119 million shares 2023-09-30 Source
Exact value

119118653 shares

Reported share-count change

2.18% · 2.54 million shares

Year-over-year change in reported shares. Splits, issuance and buybacks can affect this figure; it does not isolate employee compensation or economic dilution.

Exact inputs and evidence

116574031 shares · 2022-09-30· Source
119118653 shares · 2023-09-30· Source

Trailing twelve months

The four most recent complete quarters added together. This gives a full-year view that includes the latest quarterly results.

Revenue

60.3 million USD

2022-10-01 – 2023-09-30

Exact inputs and evidence

Revenue: 70147000 USD · 2022-01-01 – 2022-12-31 Source
Revenue: 54210000 USD · 2022-01-01 – 2022-09-30 Source
Revenue: 14086000 USD · 2023-01-01 – 2023-03-31 Source
Revenue: 15351000 USD · 2023-04-01 – 2023-06-30 Source
Revenue: 14887000 USD · 2023-07-01 – 2023-09-30 Source

Capital expenditure

36 thousand USD

2022-10-01 – 2023-09-30

Exact inputs and evidence

Capital expenditure: 167000 USD · 2022-01-01 – 2022-12-31 Source
Capital expenditure: 162000 USD · 2022-01-01 – 2022-09-30 Source
Capital expenditure: 11000 USD · 2023-01-01 – 2023-03-31 Source
Capital expenditure: 27000 USD · 2023-01-01 – 2023-06-30 Source
Capital expenditure: 11000 USD · 2023-01-01 – 2023-03-31 Source
Capital expenditure: 31000 USD · 2023-01-01 – 2023-09-30 Source
Capital expenditure: 27000 USD · 2023-01-01 – 2023-06-30 Source

Includes later revisions to earlier periods. Annual charts exclude incomplete years.

Latest filing recorded: 2023-11-07.

Financial data available through: 2022-12-31.

Coverage by financial measure

Revenue: 3 of 11 periods available· newest 2022-12-31
Operating income: 3 of 11 periods available· newest 2022-12-31
Net income: 3 of 11 periods available· newest 2022-12-31
Operating cash flow: 3 of 11 periods available· newest 2022-12-31
Capital expenditure: 3 of 11 periods available· newest 2022-12-31
Total assets: 3 of 11 periods available· newest 2022-12-31
Total liabilities: 3 of 11 periods available· newest 2022-12-31
Current assets: 3 of 11 periods available· newest 2022-12-31
Current liabilities: 3 of 11 periods available· newest 2022-12-31
Cash and cash equivalents: 3 of 11 periods available· newest 2022-12-31
long term debt: No compatible figures in this window
Shares outstanding: 3 of 11 periods available· newest 2022-12-31

Coverage describes values retained in this snapshot. Missing values are not zero; loading limits are reported separately.

What changed year over year

Latest complete year compared with the corresponding period one year earlier. These are measured changes; they do not establish their business causes.

Revenue
+17.7%

Prior period

USD 59.6 million

2021-01-01 – 2021-12-31
Current period

USD 70.15 million

2022-01-01 – 2022-12-31

Exact inputs and evidence

70147000 − 59597000 = 10550000 USD

59597000 USD · 2021-01-01 – 2021-12-31
Inspect prior input Prior source
70147000 USD · 2022-01-01 – 2022-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Revenue · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Year-over-year change in Revenue: 10550000 USD Concept: fundies:Revenue Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:Revenue: 70147000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#720518 Filing: 000181911323000009 Input fundies:Revenue: 59597000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#721804 Filing: 000181911323000009
The citation records this snapshot. The page link may show a newer release later.
Net income
+USD 43.34 million

Prior period

−USD 94.33 million

2021-01-01 – 2021-12-31
Current period

−USD 50.99 million

2022-01-01 – 2022-12-31

Exact inputs and evidence

-50988000 − -94331000 = 43343000 USD

-94331000 USD · 2021-01-01 – 2021-12-31
Inspect prior input Prior source
-50988000 USD · 2022-01-01 – 2022-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Net income · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Year-over-year change in Net income: 43343000 USD Concept: fundies:NetIncome Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:NetIncome: -50988000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#1371879 Filing: 000181911323000009 Input fundies:NetIncome: -94331000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#1373055 Filing: 000181911323000009
The citation records this snapshot. The page link may show a newer release later.
Operating cash flow
−USD 38.97 million

Prior period

−USD 36.48 million

2021-01-01 – 2021-12-31
Current period

−USD 75.44 million

2022-01-01 – 2022-12-31

Exact inputs and evidence

-75443000 − -36478000 = -38965000 USD

-36478000 USD · 2021-01-01 – 2021-12-31
Inspect prior input Prior source
-75443000 USD · 2022-01-01 – 2022-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Operating cash flow · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Year-over-year change in Operating cash flow: -38965000 USD Concept: fundies:OperatingCashFlow Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:OperatingCashFlow: -75443000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#922008 Filing: 000181911323000009 Input fundies:OperatingCashFlow: -36478000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#923059 Filing: 000181911323000009
The citation records this snapshot. The page link may show a newer release later.
Capital expenditure
-86.4%

Prior period

USD 1.23 million

2021-01-01 – 2021-12-31
Current period

USD 167,000

2022-01-01 – 2022-12-31

Exact inputs and evidence

167000 − 1231000 = -1064000 USD

1231000 USD · 2021-01-01 – 2021-12-31
Inspect prior input Prior source
167000 USD · 2022-01-01 – 2022-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Capital expenditure · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Year-over-year change in Capital expenditure: -1064000 USD Concept: fundies:CapitalExpenditure Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:CapitalExpenditure: 167000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927019 Filing: 000181911323000009 Input fundies:CapitalExpenditure: 1231000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927977 Filing: 000181911323000009
The citation records this snapshot. The page link may show a newer release later.

Where revenue goes

How a period’s revenue divides into costs and what remains as profit. Items marked Derived are calculated by subtraction from reported figures.

2022 2022-01-01 – 2022-12-31

Revenue USD 70.15 million 100% of revenue
Operating costs Derived USD 222.18 million 317% of revenue
Operating income −USD 152.03 million −217% of revenue
Tax, interest and other Derived −USD 101.05 million −144% of revenue
Net income −USD 50.99 million −73% of revenue

Cash

Operating cash flow −USD 75.44 million −108% of revenue
Capital expenditure USD 167,000 0.2% of revenue
Free cash flow Derived −USD 75.61 million −108% of revenue

Share of revenue by period

Net income
Tax, interest and other
Operating costs

2020 Operating loss: operating costs were 237% of revenue.
2021 Operating loss: operating costs were 207% of revenue.
2022 Operating loss: operating costs were 317% of revenue.

Values and sources

Revenue breakdown by annual reporting period
Period	Revenue	Operating costs	Operating income	Tax, interest and other	Net income	Free cash flow	Source
2020 2020-01-01 – 2020-12-31	23704000	56167000 Derived	-32463000	-789000 Derived	-31674000	-25828000 Derived	Source 2020-01-01 – 2020-12-31: 23704000 USD Inspect Revenue Open source 2020-01-01 – 2020-12-31: -32463000 USD Inspect Operating Income Open source 2020-01-01 – 2020-12-31: -31674000 USD Inspect Net Income Open source 2020-01-01 – 2020-12-31: -25476000 USD Inspect Operating Cash Flow Open source 2020-01-01 – 2020-12-31: 352000 USD Inspect Capital Expenditure Open source
2021 2021-01-01 – 2021-12-31	59597000	123315000 Derived	-63718000	30613000 Derived	-94331000	-37709000 Derived	Source 2021-01-01 – 2021-12-31: 59597000 USD Inspect Revenue Open source 2021-01-01 – 2021-12-31: -63718000 USD Inspect Operating Income Open source 2021-01-01 – 2021-12-31: -94331000 USD Inspect Net Income Open source 2021-01-01 – 2021-12-31: -36478000 USD Inspect Operating Cash Flow Open source 2021-01-01 – 2021-12-31: 1231000 USD Inspect Capital Expenditure Open source
2022 2022-01-01 – 2022-12-31	70147000	222181000 Derived	-152034000	-101046000 Derived	-50988000	-75610000 Derived	Source 2022-01-01 – 2022-12-31: 70147000 USD Inspect Revenue Open source 2022-01-01 – 2022-12-31: -152034000 USD Inspect Operating Income Open source 2022-01-01 – 2022-12-31: -50988000 USD Inspect Net Income Open source 2022-01-01 – 2022-12-31: -75443000 USD Inspect Operating Cash Flow Open source 2022-01-01 – 2022-12-31: 167000 USD Inspect Capital Expenditure Open source

Amounts are exact, in USD.

Growth

Sales over time and how quickly they are changing.

Revenue

Revenue reported for each complete financial period.

USD 70.1M 2022

Values and sources

Revenue values and source evidence
Period	Series	Value(USD)	Source evidence
20202020-12-31	Revenue	23704000	Revenue: 23704000 Open source
20212021-12-31	Revenue	59597000	Revenue: 59597000 Open source
20222022-12-31	Revenue	70147000	Revenue: 70147000 Open source

Revenue growth

Change in revenue from the same financial period one year earlier.

17.7% 2022

Values and sources

Revenue growth values and source evidence
Period	Series	Value	Source evidence
20202020-12-31	Year over year	No prior comparable period	Revenue: 23704000 Open source
20212021-12-31	Year over year	151.4%	Revenue: 59597000 Open source Revenue: 23704000 Open source
20222022-12-31	Year over year	17.7%	Revenue: 70147000 Open source Revenue: 59597000 Open source

Profit and cash

How much revenue becomes profit, and how much cash operations generate.

Profit margins

Operating income, net income and free cash flow as a share of revenue.

Operating margin -216.7% 2022

Net margin -72.7% 2022

Free cash flow margin -107.8% 2022

Operating margin
Net margin
Free cash flow margin

Values and sources

Profit margins values and source evidence
Period	Series	Value	Source evidence
20202020-12-31	Operating margin	-137%	Operating Income: -32463000 Open source Revenue: 23704000 Open source
20212021-12-31	Operating margin	-106.9%	Operating Income: -63718000 Open source Revenue: 59597000 Open source
20222022-12-31	Operating margin	-216.7%	Operating Income: -152034000 Open source Revenue: 70147000 Open source
20202020-12-31	Net margin	-133.6%	Net Income: -31674000 Open source Revenue: 23704000 Open source
20212021-12-31	Net margin	-158.3%	Net Income: -94331000 Open source Revenue: 59597000 Open source
20222022-12-31	Net margin	-72.7%	Net Income: -50988000 Open source Revenue: 70147000 Open source
20202020-12-31	Free cash flow margin	-109%	Revenue: 23704000 Open source Operating Cash Flow: -25476000 Open source Capital Expenditure: 352000 Open source
20212021-12-31	Free cash flow margin	-63.3%	Revenue: 59597000 Open source Operating Cash Flow: -36478000 Open source Capital Expenditure: 1231000 Open source
20222022-12-31	Free cash flow margin	-107.8%	Revenue: 70147000 Open source Operating Cash Flow: -75443000 Open source Capital Expenditure: 167000 Open source

Operating cash flow

Cash generated by the company’s normal business operations.

USD -75.4M 2022

Values and sources

Operating cash flow values and source evidence
Period	Series	Value(USD)	Source evidence
20202020-12-31	Operating cash flow	-25476000	Operating Cash Flow: -25476000 Open source
20212021-12-31	Operating cash flow	-36478000	Operating Cash Flow: -36478000 Open source
20222022-12-31	Operating cash flow	-75443000	Operating Cash Flow: -75443000 Open source

Free cash flow

Operating cash flow minus capital expenditure for the same period and unit.

USD -75.6M 2022

Values and sources

Free cash flow values and source evidence
Period	Series	Value(USD)	Source evidence
20202020-12-31	Free cash flow	-25828000	Operating Cash Flow: -25476000 Open source Capital Expenditure: 352000 Open source
20212021-12-31	Free cash flow	-37709000	Operating Cash Flow: -36478000 Open source Capital Expenditure: 1231000 Open source
20222022-12-31	Free cash flow	-75610000	Operating Cash Flow: -75443000 Open source Capital Expenditure: 167000 Open source

Balance sheet

Liabilities and short-term ability to meet obligations at each period end.

Liabilities to assets

Total liabilities as a share of total assets.

23% 2022

Values and sources

Liabilities to assets values and source evidence
Period	Series	Value	Source evidence
20202020-12-31	Liabilities / assets	35.2%	Total Liabilities: 20080000 Open source Total Assets: 57031000 Open source
20212021-12-31	Liabilities / assets	53.4%	Total Liabilities: 139199000 Open source Total Assets: 260798000 Open source
20222022-12-31	Liabilities / assets	23%	Total Liabilities: 29062000 Open source Total Assets: 126448000 Open source

Current assets to current liabilities

Current assets divided by current liabilities.

5.45× 2022

Values and sources

Current assets to current liabilities values and source evidence
Period	Series	Value	Source evidence
20202020-12-31	Current assets / current liabilities	2.52×	Current Assets: 46048000 Open source Current Liabilities: 18301000 Open source
20212021-12-31	Current assets / current liabilities	6.64×	Current Assets: 232703000 Open source Current Liabilities: 35022000 Open source
20222022-12-31	Current assets / current liabilities	5.45×	Current Assets: 126204000 Open source Current Liabilities: 23176000 Open source

Cash generation

Compare reported profit with operating cash and capital spending. Free cash flow is calculated as operating cash flow minus capital expenditure when both exact, consolidated amounts match the same period and unit.

Cash generation by annual reporting period
Period	Net income	Operating cash flow	Capital expenditure	Free cash flow
2020 2020-01-01 – 2020-12-31	−USD 31.67 million Exact value Exact value: -31674000 USD 2020-01-01 – 2020-12-31: -31674000 USD Inspect Net Income Open source Share or cite Citation for Net Income · SCIENCE 37 HOLDINGS, INC. · 2020-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Net Income: -31674000 USD Concept: fundies:NetIncome Period: 2020-01-01 to 2020-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ANetIncome&period=2020-12-31&surface=latest&period_type=duration&start=2020-01-01&unit=USD&dimensions= Input fundies:NetIncome: -31674000 USD (2020-01-01 to 2020-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911322000011/snce-20211231.htm#1436348 Filing: 000181911322000011 The citation records this snapshot. The page link may show a newer release later.	−USD 25.48 million Exact value Exact value: -25476000 USD 2020-01-01 – 2020-12-31: -25476000 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · SCIENCE 37 HOLDINGS, INC. · 2020-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Operating Cash Flow: -25476000 USD Concept: fundies:OperatingCashFlow Period: 2020-01-01 to 2020-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3AOperatingCashFlow&period=2020-12-31&surface=latest&period_type=duration&start=2020-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -25476000 USD (2020-01-01 to 2020-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911322000011/snce-20211231.htm#1001218 Filing: 000181911322000011 The citation records this snapshot. The page link may show a newer release later.	USD 352,000 Exact value Exact value: 352000 USD 2020-01-01 – 2020-12-31: 352000 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · SCIENCE 37 HOLDINGS, INC. · 2020-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Capital Expenditure: 352000 USD Concept: fundies:CapitalExpenditure Period: 2020-01-01 to 2020-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ACapitalExpenditure&period=2020-12-31&surface=latest&period_type=duration&start=2020-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 352000 USD (2020-01-01 to 2020-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911322000011/snce-20211231.htm#1006101 Filing: 000181911322000011 The citation records this snapshot. The page link may show a newer release later.	−USD 25.83 million Calculation and evidence -25476000 − 352000 USD Exact free cash flow: -25828000 USD 2020-01-01 – 2020-12-31: -25476000 USD · Inspect Operating Cash Flow · Source 2020-01-01 – 2020-12-31: 352000 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · SCIENCE 37 HOLDINGS, INC. · 2020-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Free cash flow: -25828000 USD Concept: free-cash-flow Period: 2020-01-01 to 2020-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -25476000 USD (2020-01-01 to 2020-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911322000011/snce-20211231.htm#1001218 Filing: 000181911322000011 Input fundies:CapitalExpenditure: 352000 USD (2020-01-01 to 2020-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911322000011/snce-20211231.htm#1006101 Filing: 000181911322000011 The citation records this snapshot. The page link may show a newer release later.
2021 2021-01-01 – 2021-12-31	−USD 94.33 million Exact value Exact value: -94331000 USD 2021-01-01 – 2021-12-31: -94331000 USD Inspect Net Income Open source Share or cite Citation for Net Income · SCIENCE 37 HOLDINGS, INC. · 2021-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Net Income: -94331000 USD Concept: fundies:NetIncome Period: 2021-01-01 to 2021-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ANetIncome&period=2021-12-31&surface=latest&period_type=duration&start=2021-01-01&unit=USD&dimensions= Input fundies:NetIncome: -94331000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#1373055 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	−USD 36.48 million Exact value Exact value: -36478000 USD 2021-01-01 – 2021-12-31: -36478000 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · SCIENCE 37 HOLDINGS, INC. · 2021-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Operating Cash Flow: -36478000 USD Concept: fundies:OperatingCashFlow Period: 2021-01-01 to 2021-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3AOperatingCashFlow&period=2021-12-31&surface=latest&period_type=duration&start=2021-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -36478000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#923059 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	USD 1.23 million Exact value Exact value: 1231000 USD 2021-01-01 – 2021-12-31: 1231000 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · SCIENCE 37 HOLDINGS, INC. · 2021-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Capital Expenditure: 1231000 USD Concept: fundies:CapitalExpenditure Period: 2021-01-01 to 2021-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ACapitalExpenditure&period=2021-12-31&surface=latest&period_type=duration&start=2021-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 1231000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927977 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	−USD 37.71 million Calculation and evidence -36478000 − 1231000 USD Exact free cash flow: -37709000 USD 2021-01-01 – 2021-12-31: -36478000 USD · Inspect Operating Cash Flow · Source 2021-01-01 – 2021-12-31: 1231000 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · SCIENCE 37 HOLDINGS, INC. · 2021-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Free cash flow: -37709000 USD Concept: free-cash-flow Period: 2021-01-01 to 2021-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -36478000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#923059 Filing: 000181911323000009 Input fundies:CapitalExpenditure: 1231000 USD (2021-01-01 to 2021-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927977 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.
2022 2022-01-01 – 2022-12-31	−USD 50.99 million Exact value Exact value: -50988000 USD 2022-01-01 – 2022-12-31: -50988000 USD Inspect Net Income Open source Share or cite Citation for Net Income · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Net Income: -50988000 USD Concept: fundies:NetIncome Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ANetIncome&period=2022-12-31&surface=latest&period_type=duration&start=2022-01-01&unit=USD&dimensions= Input fundies:NetIncome: -50988000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#1371879 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	−USD 75.44 million Exact value Exact value: -75443000 USD 2022-01-01 – 2022-12-31: -75443000 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Operating Cash Flow: -75443000 USD Concept: fundies:OperatingCashFlow Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3AOperatingCashFlow&period=2022-12-31&surface=latest&period_type=duration&start=2022-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -75443000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#922008 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	USD 167,000 Exact value Exact value: 167000 USD 2022-01-01 – 2022-12-31: 167000 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Capital Expenditure: 167000 USD Concept: fundies:CapitalExpenditure Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113/explain?concept=fundies%3ACapitalExpenditure&period=2022-12-31&surface=latest&period_type=duration&start=2022-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 167000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927019 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.	−USD 75.61 million Calculation and evidence -75443000 − 167000 USD Exact free cash flow: -75610000 USD 2022-01-01 – 2022-12-31: -75443000 USD · Inspect Operating Cash Flow · Source 2022-01-01 – 2022-12-31: 167000 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · SCIENCE 37 HOLDINGS, INC. · 2022-12-31 SCIENCE 37 HOLDINGS, INC. (edgar:1819113) Free cash flow: -75610000 USD Concept: free-cash-flow Period: 2022-01-01 to 2022-12-31 Values: Latest reported Published: 2026-11-02T20:12:39Z Snapshot: 5b8e5e0edbba26e80b62de1108c1a741934370427466d1bc0f68d3c4b9b8e7e2 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1819113?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -75443000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#922008 Filing: 000181911323000009 Input fundies:CapitalExpenditure: 167000 USD (2022-01-01 to 2022-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1819113/000181911323000009/snce-20221231.htm#927019 Filing: 000181911323000009 The citation records this snapshot. The page link may show a newer release later.

Capital expenditure uses the canonical mapped positive-spending convention. A missing, ambiguous, incompatible, or negative-sign input is left blank. Values use the latest reported version.

Dataset coverage and company identifiers

Coverage reflects filings processed into this Fundies dataset; it does not imply every source filing is loaded.

19 filings · 1,286 latest values · 1,286 originally reported values

Dataset published 2026-11-02. Source filing dates and reporting periods are shown separately.

Identifiers: 0001819113, 1819113, LSAQ, SNCE, edgar:1819113

Also known as LIFESCI ACQUISITION II CORP., Lifesci Acquisition II Corp., SCIENCE 37 HOLDINGS, INC., Science 37 Holdings, Inc.

SCIENCE 37 HOLDINGS, INC.

Latest quarter

Revenue

Operating margin

Operating cash flow

Free cash flow

Reported share-count change

Trailing twelve months

Revenue

Capital expenditure

Company performance

What changed year over year

Revenue

Net income

Operating cash flow

Capital expenditure

Where revenue goes

2022 2022-01-01 – 2022-12-31

Cash

Share of revenue by period

Growth

Profit and cash

Balance sheet

Cash generation