SPERO THERAPEUTICS, INC.

EDGAR

Annual consolidated revenue for 2025: about USD 66.8M, using the latest reported figures. The previous period, 2024, was about USD 47.98M.

Watchlist

Latest quarter

Revenue

0 USD

2026 Q2 · USD

Exact inputs and evidence

Operating cash flow

-5.36 million USD

2026 Q2 · USD

Exact inputs and evidence
  • Operating Cash Flow: 10509000 USD Source
  • Operating Cash Flow: 15864000 USD Source
Cash and cash equivalents
50.8 million USD Source
Exact value

50774000 USD

Long-term debt including current maturities
Not available
Shares outstanding
58.1 million shares Source
Exact value

58146910 shares

Reported share-count change

3.49% · 1.96 million shares

Year-over-year change in reported shares. Splits, issuance and buybacks can affect this figure; it does not isolate employee compensation or economic dilution.

Exact inputs and evidence
  • 56187308 shares · 2025-06-30· Source
  • 58146910 shares · 2026-06-30· Source

Trailing twelve months

The four most recent complete quarters added together. This gives a full-year view that includes the latest quarterly results.

Revenue

47 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Revenue: 5442000 USD · 2025-07-01 – 2025-09-30 Source
  • Revenue: 66802000 USD · 2025-01-01 – 2025-12-31 Source
  • Revenue: 25505000 USD · 2025-01-01 – 2025-09-30 Source
  • Revenue: 258000 USD · 2026-01-01 – 2026-03-31 Source
  • Revenue: 0 USD · 2026-04-01 – 2026-06-30 Source

Net income

7.38 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Net income: -7382000 USD · 2025-07-01 – 2025-09-30 Source
  • Net income: 8572000 USD · 2025-01-01 – 2025-12-31 Source
  • Net income: -22948000 USD · 2025-01-01 – 2025-09-30 Source
  • Net income: -7203000 USD · 2026-01-01 – 2026-03-31 Source
  • Net income: -9552000 USD · 2026-04-01 – 2026-06-30 Source

Operating cash flow

19.6 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Operating cash flow: -4273000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: -21695000 USD · 2025-01-01 – 2025-06-30 Source
  • Operating cash flow: -12624000 USD · 2025-01-01 – 2025-12-31 Source
  • Operating cash flow: -4273000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: 15864000 USD · 2026-01-01 – 2026-03-31 Source
  • Operating cash flow: 10509000 USD · 2026-01-01 – 2026-06-30 Source
  • Operating cash flow: 15864000 USD · 2026-01-01 – 2026-03-31 Source

Company performance

Up to ten complete financial years · consolidated figures

Includes later revisions to earlier periods. Annual charts exclude incomplete years.

Latest filing recorded: 2026-10-27.

Financial data available through: 2025-12-31.

Coverage by financial measure
  • Revenue: 10 of 11 periods available· newest 2025-12-31
  • Operating income: 11 of 11 periods available· newest 2025-12-31
  • Net income: 10 of 11 periods available· newest 2025-12-31
  • Operating cash flow: 11 of 11 periods available· newest 2025-12-31
  • Capital expenditure: 6 of 11 periods available· newest 2020-12-31
  • Total assets: 10 of 11 periods available· newest 2025-12-31
  • Total liabilities: 10 of 11 periods available· newest 2025-12-31
  • Current assets: 10 of 11 periods available· newest 2025-12-31
  • Current liabilities: 10 of 11 periods available· newest 2025-12-31
  • Cash and cash equivalents: 10 of 11 periods available· newest 2025-12-31
  • long term debt: No compatible figures in this window
  • Shares outstanding: 10 of 11 periods available· newest 2025-12-31

Coverage describes values retained in this snapshot. Missing values are not zero; loading limits are reported separately.

What changed year over year

Latest complete year compared with the corresponding period one year earlier. These are measured changes; they do not establish their business causes.

  • Revenue

    +39.2%

    Prior period

    USD 47.98 million

    –

    Current period

    USD 66.8 million

    –

    Exact inputs and evidence

    66802000 − 47977000 = 18825000 USD

    47977000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    66802000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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  • Net income

    +USD 77.14 million

    Prior period

    −USD 68.57 million

    –

    Current period

    USD 8.57 million

    –

    Exact inputs and evidence

    8572000 − -68566000 = 77138000 USD

    -68566000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    8572000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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  • Operating cash flow

    +USD 10.82 million

    Prior period

    −USD 23.44 million

    –

    Current period

    −USD 12.62 million

    –

    Exact inputs and evidence

    -12624000 − -23444000 = 10820000 USD

    -23444000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    -12624000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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Comparable inputs unavailable for: Capital expenditure.

Where revenue goes

How a period’s revenue divides into costs and what remains as profit. Items marked Derived are calculated by subtraction from reported figures.

2025 2025-01-01 – 2025-12-31

  • Revenue USD 66.8 million 100% of revenue
  • Operating costs Derived USD 60.49 million 91% of revenue
  • Operating income USD 6.31 million 9.5% of revenue
  • Tax, interest and other Derived −USD 2.26 million −3.4% of revenue
  • Net income USD 8.57 million 13% of revenue

Cash

  • Operating cash flow −USD 12.62 million −19% of revenue
  • Capital expenditure Unavailable An input is unavailable.
  • Free cash flow Derived Unavailable An input is unavailable.

Share of revenue by period

  • Net income
  • Tax, interest and other
  • Operating costs
  • 2016 Operating loss: operating costs were 10,017% of revenue.
  • 2017 Operating loss: operating costs were 2,209% of revenue.
  • 2018 Operating loss: operating costs were 1,179% of revenue.
  • 2019 Operating loss: operating costs were 448% of revenue.
  • 2020 Operating loss: operating costs were 948% of revenue.
  • 2021 Operating loss: operating costs were 582% of revenue.
  • 2022 Not shown: operating income or net income is not reported.
  • 2023 Net income was higher than operating income, so the split is not drawn.
  • 2024 Operating loss: operating costs were 253% of revenue.
  • 2025 Net income was higher than operating income, so the split is not drawn.
Values and sources
Revenue breakdown by annual reporting period
PeriodRevenueOperating costsOperating incomeTax, interest and otherNet incomeFree cash flowSource
2016 2016-01-01 – 2016-12-31335000 33556000 Derived -33221000 -7730000 Derived -25491000 -29789000 Derived
Source
2017 2017-01-01 – 2017-12-311979000 43709000 Derived -41730000 -2987000 Derived -38743000 -39138000 Derived
Source
2018 2018-01-01 – 2018-12-313966000 46772000 Derived -42806000 -1106000 Derived -41700000 -42061000 Derived
Source
2019 2019-01-01 – 2019-12-3118147000 81363000 Derived -63216000 -2316000 Derived -60900000 -50334000 Derived
Source
2020 2020-01-01 – 2020-12-319330000 88443000 Derived -79113000 -813000 Derived -78300000 -86029000 Derived
Source
2021 2021-01-01 – 2021-12-3118256000 106227000 Derived -87971000 1829000 Derived -89800000 Unavailable
Source
2022 2022-01-01 – 2022-12-3153509000 95706000 Derived -42197000 UnavailableUnavailableUnavailable
Source
2023 2023-01-01 – 2023-12-31103781000 82300000 Derived 21481000 -1325000 Derived 22806000 Unavailable
Source
2024 2024-01-01 – 2024-12-3147977000 121338000 Derived -73361000 -4795000 Derived -68566000 Unavailable
Source
2025 2025-01-01 – 2025-12-3166802000 60488000 Derived 6314000 -2258000 Derived 8572000 Unavailable
Source

Amounts are exact, in USD.

Growth

Sales over time and how quickly they are changing.

Revenue

Revenue reported for each complete financial period.

USD 66.8M 2025
Revenue historyRevenue reported for each complete financial period. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.112.1M84.1M56.0M28.0M0.0201620212025
Values and sources
Revenue values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Revenue335000
2017Revenue1979000
2018Revenue3966000
2019Revenue18147000
2020Revenue9330000
2021Revenue18256000
2022Revenue53509000
2023Revenue103781000
2024Revenue47977000
2025Revenue66802000

Revenue growth

Change in revenue from the same financial period one year earlier.

39.2% 2025
Revenue growth historyChange in revenue from the same financial period one year earlier. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.534%376%218%61%-97%201620212025
Values and sources
Revenue growth values and source evidence
PeriodSeriesValueSource evidence
2016Year over yearNo prior comparable period
2017Year over year490.7%
2018Year over year100.4%
2019Year over year357.6%
2020Year over year-48.6%
2021Year over year95.7%
2022Year over year193.1%
2023Year over year94%
2024Year over year-53.8%
2025Year over year39.2%

Profit and cash

How much revenue becomes profit, and how much cash operations generate.

Profit margins

Operating income, net income and free cash flow as a share of revenue.

Operating margin 9.5% 2025
Net margin 12.8% 2025
Free cash flow margin -922.1% 2020
Profit margins historyOperating income, net income and free cash flow as a share of revenue. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.817%-2,065%-4,947%-7,830%-10,712%201620212025
  • Operating margin
  • Net margin
  • Free cash flow margin
Values and sources
Profit margins values and source evidence
PeriodSeriesValueSource evidence
2016Operating margin-9,916.7%
2017Operating margin-2,108.6%
2018Operating margin-1,079.3%
2019Operating margin-348.4%
2020Operating margin-847.9%
2021Operating margin-481.9%
2022Operating margin-78.9%
2023Operating margin20.7%
2024Operating margin-152.9%
2025Operating margin9.5%
2016Net margin-7,609.3%
2017Net margin-1,957.7%
2018Net margin-1,051.4%
2019Net margin-335.6%
2020Net margin-839.2%
2021Net margin-491.9%
2022-12-31Net marginNot reported
2023Net margin22%
2024Net margin-142.9%
2025Net margin12.8%
2016Free cash flow margin-8,892.2%
2017Free cash flow margin-1,977.7%
2018Free cash flow margin-1,060.5%
2019Free cash flow margin-277.4%
2020Free cash flow margin-922.1%
2021Free cash flow marginNot reported
2022Free cash flow marginNot reported
2023Free cash flow marginNot reported
2024Free cash flow marginNot reported
2025Free cash flow marginNot reported

Operating cash flow

Cash generated by the company’s normal business operations.

USD -12.6M 2025
Operating cash flow historyCash generated by the company’s normal business operations. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.6.9M-18.0M-42.9M-67.8M-92.7M201620212025
Values and sources
Operating cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Operating cash flow-28959000
2017Operating cash flow-39111000
2018Operating cash flow-39625000
2019Operating cash flow-50020000
2020Operating cash flow-85872000
2021Operating cash flow-64347000
2022Operating cash flow-7731000
2023Operating cash flow-32995000
2024Operating cash flow-23444000
2025Operating cash flow-12624000

Free cash flow

Operating cash flow minus capital expenditure for the same period and unit.

USD -86M 2020
Free cash flow historyOperating cash flow minus capital expenditure for the same period and unit. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.6.9M-18.1M-43.0M-68.0M-92.9M201620212025
Values and sources
Free cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Free cash flow-29789000
2017Free cash flow-39138000
2018Free cash flow-42061000
2019Free cash flow-50334000
2020Free cash flow-86029000
2021Free cash flowUnavailable
2022Free cash flowUnavailable
2023Free cash flowUnavailable
2024Free cash flowUnavailable
2025Free cash flowUnavailable

Balance sheet

Liabilities and short-term ability to meet obligations at each period end.

Liabilities to assets

Total liabilities as a share of total assets.

14.4% 2025
Liabilities to assets historyTotal liabilities as a share of total assets. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.63%47%31%16%0%201620212025
Values and sources
Liabilities to assets values and source evidence
PeriodSeriesValueSource evidence
2016Liabilities / assets53.8%
2017Liabilities / assets9.1%
2018Liabilities / assets10.2%
2019Liabilities / assets29.7%
2020Liabilities / assets14%
2021Liabilities / assets48.4%
2022Liabilities / assets39.2%
2023Liabilities / assets41.4%
2024Liabilities / assets58.3%
2025Liabilities / assets14.4%

Current assets to current liabilities

Current assets divided by current liabilities.

7.59× 2025
Current assets to current liabilities historyCurrent assets divided by current liabilities. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.12.19×9.14×6.09×3.05×0.00×201620212025
Values and sources
Current assets to current liabilities values and source evidence
PeriodSeriesValueSource evidence
2016Current assets / current liabilities1.72×
2017Current assets / current liabilities11.29×
2018Current assets / current liabilities10.08×
2019Current assets / current liabilities3.58×
2020Current assets / current liabilities9.7×
2021Current assets / current liabilities8.46×
2022Current assets / current liabilities5.25×
2023Current assets / current liabilities3.53×
2024Current assets / current liabilities2.19×
2025Current assets / current liabilities7.59×

Cash generation

Compare reported profit with operating cash and capital spending. Free cash flow is calculated as operating cash flow minus capital expenditure when both exact, consolidated amounts match the same period and unit.

Cash generation by annual reporting period
PeriodNet incomeOperating cash flowCapital expenditureFree cash flow
2016 2016-01-01 – 2016-12-31
−USD 25.49 million
Exact value

Exact value: -25491000 USD

2016-01-01 – 2016-12-31: -25491000 USD Inspect Net Income Open source
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−USD 28.96 million
Exact value

Exact value: -28959000 USD

2016-01-01 – 2016-12-31: -28959000 USD Inspect Operating Cash Flow Open source
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USD 830,000
Exact value

Exact value: 830000 USD

2016-01-01 – 2016-12-31: 830000 USD Inspect Capital Expenditure Open source
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−USD 29.79 million
Calculation and evidence

-28959000 − 830000 USD

Exact free cash flow: -29789000 USD

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2017 2017-01-01 – 2017-12-31
−USD 38.74 million
Exact value

Exact value: -38743000 USD

2017-01-01 – 2017-12-31: -38743000 USD Inspect Net Income Open source
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−USD 39.11 million
Exact value

Exact value: -39111000 USD

2017-01-01 – 2017-12-31: -39111000 USD Inspect Operating Cash Flow Open source
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USD 27,000
Exact value

Exact value: 27000 USD

2017-01-01 – 2017-12-31: 27000 USD Inspect Capital Expenditure Open source
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−USD 39.14 million
Calculation and evidence

-39111000 − 27000 USD

Exact free cash flow: -39138000 USD

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2018 2018-01-01 – 2018-12-31
−USD 41.7 million
Exact value

Exact value: -41700000 USD

2018-01-01 – 2018-12-31: -41700000 USD Inspect Net Income Open source
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−USD 39.63 million
Exact value

Exact value: -39625000 USD

2018-01-01 – 2018-12-31: -39625000 USD Inspect Operating Cash Flow Open source
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USD 2.44 million
Exact value

Exact value: 2436000 USD

2018-01-01 – 2018-12-31: 2436000 USD Inspect Capital Expenditure Open source
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−USD 42.06 million
Calculation and evidence

-39625000 − 2436000 USD

Exact free cash flow: -42061000 USD

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2019 2019-01-01 – 2019-12-31
−USD 60.9 million
Exact value

Exact value: -60900000 USD

2019-01-01 – 2019-12-31: -60900000 USD Inspect Net Income Open source
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−USD 50.02 million
Exact value

Exact value: -50020000 USD

2019-01-01 – 2019-12-31: -50020000 USD Inspect Operating Cash Flow Open source
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USD 314,000
Exact value

Exact value: 314000 USD

2019-01-01 – 2019-12-31: 314000 USD Inspect Capital Expenditure Open source
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−USD 50.33 million
Calculation and evidence

-50020000 − 314000 USD

Exact free cash flow: -50334000 USD

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2020 2020-01-01 – 2020-12-31
−USD 78.3 million
Exact value

Exact value: -78300000 USD

2020-01-01 – 2020-12-31: -78300000 USD Inspect Net Income Open source
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−USD 85.87 million
Exact value

Exact value: -85872000 USD

2020-01-01 – 2020-12-31: -85872000 USD Inspect Operating Cash Flow Open source
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USD 157,000
Exact value

Exact value: 157000 USD

2020-01-01 – 2020-12-31: 157000 USD Inspect Capital Expenditure Open source
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−USD 86.03 million
Calculation and evidence

-85872000 − 157000 USD

Exact free cash flow: -86029000 USD

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2021 2021-01-01 – 2021-12-31
−USD 89.8 million
Exact value

Exact value: -89800000 USD

2021-01-01 – 2021-12-31: -89800000 USD Inspect Net Income Open source
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−USD 64.35 million
Exact value

Exact value: -64347000 USD

2021-01-01 – 2021-12-31: -64347000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2022 2022-01-01 – 2022-12-31
Unavailable Not reported for this period.
−USD 7.73 million
Exact value

Exact value: -7731000 USD

2022-01-01 – 2022-12-31: -7731000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2023 2023-01-01 – 2023-12-31
USD 22.81 million
Exact value

Exact value: 22806000 USD

2023-01-01 – 2023-12-31: 22806000 USD Inspect Net Income Open source
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−USD 33 million
Exact value

Exact value: -32995000 USD

2023-01-01 – 2023-12-31: -32995000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2024 2024-01-01 – 2024-12-31
−USD 68.57 million
Exact value

Exact value: -68566000 USD

2024-01-01 – 2024-12-31: -68566000 USD Inspect Net Income Open source
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−USD 23.44 million
Exact value

Exact value: -23444000 USD

2024-01-01 – 2024-12-31: -23444000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2025 2025-01-01 – 2025-12-31
USD 8.57 million
Exact value

Exact value: 8572000 USD

2025-01-01 – 2025-12-31: 8572000 USD Inspect Net Income Open source
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−USD 12.62 million
Exact value

Exact value: -12624000 USD

2025-01-01 – 2025-12-31: -12624000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

Capital expenditure uses the canonical mapped positive-spending convention. A missing, ambiguous, incompatible, or negative-sign input is left blank. Values use the latest reported version.

Dataset coverage and company identifiers

Coverage reflects filings processed into this Fundies dataset; it does not imply every source filing is loaded.

46 filings · 2,383 latest values · 2,368 originally reported values

Dataset published . Source filing dates and reporting periods are shown separately.

Identifiers: 0001701108, 1701108, SPRO, edgar:1701108

Also known as SPERO THERAPEUTICS, INC., Spero Therapeutics, Inc., Spero Therapeutics, LLC