Syndax Pharmaceuticals Inc

EDGAR

Annual consolidated revenue for 2025: about USD 172.4M, using the latest reported figures. The previous period, 2024, was about USD 23.68M.

Watchlist

Latest quarter

Revenue

72.8 million USD

2026 Q2 · USD

Exact inputs and evidence

Operating margin

-54.95%

2026 Q2 · %

Exact inputs and evidence
  • Operating Income: -39995000 USD Source
  • Revenue: 72788000 USD Source

Operating cash flow

-30.3 million USD

2026 Q2 · USD

Exact inputs and evidence
  • Operating Cash Flow: -80617000 USD Source
  • Operating Cash Flow: -50345000 USD Source
Cash and cash equivalents
336 million USD Source
Exact value

336477000 USD

Long-term debt including current maturities
Not available
Shares outstanding
89.2 million shares Source
Exact value

89150619 shares

Reported share-count change

3.59% · 3.09 million shares

Year-over-year change in reported shares. Splits, issuance and buybacks can affect this figure; it does not isolate employee compensation or economic dilution.

Exact inputs and evidence
  • 86059077 shares · 2025-06-30· Source
  • 89150619 shares · 2026-06-30· Source

Trailing twelve months

The four most recent complete quarters added together. This gives a full-year view that includes the latest quarterly results.

Revenue

252 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Revenue: 45871000 USD · 2025-07-01 – 2025-09-30 Source
  • Revenue: 172352000 USD · 2025-01-01 – 2025-12-31 Source
  • Revenue: 103624000 USD · 2025-01-01 – 2025-09-30 Source
  • Revenue: 64864000 USD · 2026-01-01 – 2026-03-31 Source
  • Revenue: 72788000 USD · 2026-04-01 – 2026-06-30 Source

Net income

-221 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Net income: -60715000 USD · 2025-07-01 – 2025-09-30 Source
  • Net income: -285422000 USD · 2025-01-01 – 2025-12-31 Source
  • Net income: -217408000 USD · 2025-01-01 – 2025-09-30 Source
  • Net income: -42673000 USD · 2026-01-01 – 2026-03-31 Source
  • Net income: -49363000 USD · 2026-04-01 – 2026-06-30 Source

Operating cash flow

-221 million USD

2025-07-01 – 2026-06-30

Exact inputs and evidence
  • Operating cash flow: -253492000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: -182957000 USD · 2025-01-01 – 2025-06-30 Source
  • Operating cash flow: -322980000 USD · 2025-01-01 – 2025-12-31 Source
  • Operating cash flow: -253492000 USD · 2025-01-01 – 2025-09-30 Source
  • Operating cash flow: -50345000 USD · 2026-01-01 – 2026-03-31 Source
  • Operating cash flow: -80617000 USD · 2026-01-01 – 2026-06-30 Source
  • Operating cash flow: -50345000 USD · 2026-01-01 – 2026-03-31 Source

Capital expenditure

187 thousand USD

2018-01-01 – 2018-12-31

Exact inputs and evidence
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-03-31 Source
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-06-30 Source
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-03-31 Source
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-09-30 Source
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-06-30 Source
  • Capital expenditure: 187000 USD · 2018-01-01 – 2018-12-31 Source
  • Capital expenditure: 173000 USD · 2018-01-01 – 2018-09-30 Source

Company performance

Up to ten complete financial years · consolidated figures

Includes later revisions to earlier periods. Annual charts exclude incomplete years.

Latest filing recorded: 2026-08-04.

Financial data available through: 2025-12-31.

Coverage by financial measure
  • Revenue: 11 of 11 periods available· newest 2025-12-31
  • Operating income: 11 of 11 periods available· newest 2025-12-31
  • Net income: 11 of 11 periods available· newest 2025-12-31
  • Operating cash flow: 11 of 11 periods available· newest 2025-12-31
  • Capital expenditure: 10 of 11 periods available· newest 2025-12-31
  • Total assets: 11 of 11 periods available· newest 2025-12-31
  • Total liabilities: 11 of 11 periods available· newest 2025-12-31
  • Current assets: 11 of 11 periods available· newest 2025-12-31
  • Current liabilities: 11 of 11 periods available· newest 2025-12-31
  • Cash and cash equivalents: 11 of 11 periods available· newest 2025-12-31
  • long term debt: No compatible figures in this window
  • Shares outstanding: 11 of 11 periods available· newest 2025-12-31

Coverage describes values retained in this snapshot. Missing values are not zero; loading limits are reported separately.

What changed year over year

Latest complete year compared with the corresponding period one year earlier. These are measured changes; they do not establish their business causes.

  • Revenue

    +627.8%

    Prior period

    USD 23.68 million

    –

    Current period

    USD 172.35 million

    –

    Exact inputs and evidence

    172352000 − 23680000 = 148672000 USD

    23680000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    172352000 USD · 2025-01-01 – 2025-12-31

    Inspect current input Current source
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  • Net income

    +USD 33.34 million

    Prior period

    −USD 318.76 million

    –

    Current period

    −USD 285.42 million

    –

    Exact inputs and evidence

    -285422000 − -318758000 = 33336000 USD

    -318758000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    -285422000 USD · 2025-01-01 – 2025-12-31

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  • Operating cash flow

    −USD 48.08 million

    Prior period

    −USD 274.9 million

    –

    Current period

    −USD 322.98 million

    –

    Exact inputs and evidence

    -322980000 − -274903000 = -48077000 USD

    -274903000 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    -322980000 USD · 2025-01-01 – 2025-12-31

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  • Capital expenditure

    +USD 187,000

    Prior period

    USD 0

    –

    Current period

    USD 187,000

    –

    Exact inputs and evidence

    187000 − 0 = 187000 USD

    0 USD · 2024-01-01 – 2024-12-31

    Inspect prior input Prior source

    187000 USD · 2025-01-01 – 2025-12-31

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Where revenue goes

How a period’s revenue divides into costs and what remains as profit. Items marked Derived are calculated by subtraction from reported figures.

2025 2025-01-01 – 2025-12-31

  • Revenue USD 172.35 million 100% of revenue
  • Operating costs Derived USD 445.44 million 258% of revenue
  • Operating income −USD 273.08 million −158% of revenue
  • Tax, interest and other Derived USD 12.34 million 7.2% of revenue
  • Net income −USD 285.42 million −166% of revenue

Cash

  • Operating cash flow −USD 322.98 million −187% of revenue
  • Capital expenditure USD 187,000 0.1% of revenue
  • Free cash flow Derived −USD 323.17 million −188% of revenue

Share of revenue by period

  • Net income
  • Tax, interest and other
  • Operating costs
  • 2016 Operating loss: operating costs were 3,687% of revenue.
  • 2017 Operating loss: operating costs were 3,039% of revenue.
  • 2018 Operating loss: operating costs were 5,102% of revenue.
  • 2019 Operating loss: operating costs were 3,893% of revenue.
  • 2020 Operating loss: operating costs were 4,808% of revenue.
  • 2021 18%81%
  • 2022 Not shown: operating income or net income is not reported.
  • 2023 Not shown: operating income or net income is not reported.
  • 2024 Operating loss: operating costs were 1,534% of revenue.
  • 2025 Operating loss: operating costs were 258% of revenue.
Values and sources
Revenue breakdown by annual reporting period
PeriodRevenueOperating costsOperating incomeTax, interest and otherNet incomeFree cash flowSource
2016 2016-01-01 – 2016-12-311220000 44986000 Derived -43766000 706000 Derived -44472000 -35418000 Derived
Source
2017 2017-01-01 – 2017-12-312108000 64062000 Derived -61954000 -1152000 Derived -60802000 -47455000 Derived
Source
2018 2018-01-01 – 2018-12-311517000 77393000 Derived -75876000 -1915000 Derived -73961000 -68718000 Derived
Source
2019 2019-01-01 – 2019-12-311517000 59056000 Derived -57539000 -1492000 Derived -56047000 Unavailable
Source
2020 2020-01-01 – 2020-12-311517000 72940000 Derived -71423000 1735000 Derived -73158000 -71260000 Derived
Source
2021 2021-01-01 – 2021-12-31139709000 113489000 Derived 26220000 1294000 Derived 24926000 29002000 Derived
Source
2022 2022-01-01 – 2022-12-310 151757000 Derived -151757000 -2419000 Derived -149338000 -133675000 Derived
Source
2023 2023-01-01 – 2023-12-310 229954000 Derived -229954000 -20594000 Derived -209360000 -160601000 Derived
Source
2024 2024-01-01 – 2024-12-3123680000 363352000 Derived -339672000 -20914000 Derived -318758000 -274903000 Derived
Source
2025 2025-01-01 – 2025-12-31172352000 445436000 Derived -273084000 12338000 Derived -285422000 -323167000 Derived
Source

Amounts are exact, in USD.

Growth

Sales over time and how quickly they are changing.

Revenue

Revenue reported for each complete financial period.

USD 172.4M 2025
Revenue historyRevenue reported for each complete financial period. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.186.1M139.6M93.1M46.5M0.0201620212025
Values and sources
Revenue values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Revenue1220000
2017Revenue2108000
2018Revenue1517000
2019Revenue1517000
2020Revenue1517000
2021Revenue139709000
2022Revenue0
2023Revenue0
2024Revenue23680000
2025Revenue172352000

Revenue growth

Change in revenue from the same financial period one year earlier.

627.8% 2025
Revenue growth historyChange in revenue from the same financial period one year earlier. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.9,846%7,176%4,505%1,834%-837%201620212025
Values and sources
Revenue growth values and source evidence
PeriodSeriesValueSource evidence
2016Year over year94.6%
2017Year over year72.8%
2018Year over year-28%
2019Year over year0%
2020Year over year0%
2021Year over year9,109.6%
2022Year over year-100%
2023Year over yearNo prior comparable period
2024Year over yearNo prior comparable period
2025Year over year627.8%

Profit and cash

How much revenue becomes profit, and how much cash operations generate.

Profit margins

Operating income, net income and free cash flow as a share of revenue.

Operating margin -158.4% 2025
Net margin -165.6% 2025
Free cash flow margin -187.5% 2025
Profit margins historyOperating income, net income and free cash flow as a share of revenue. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.423%-1,034%-2,490%-3,947%-5,404%201620212025
  • Operating margin
  • Net margin
  • Free cash flow margin
Values and sources
Profit margins values and source evidence
PeriodSeriesValueSource evidence
2016Operating margin-3,587.4%
2017Operating margin-2,939%
2018Operating margin-5,001.7%
2019Operating margin-3,792.9%
2020Operating margin-4,708.2%
2021Operating margin18.8%
2022Operating marginNot reported
2023Operating marginNot reported
2024Operating margin-1,434.4%
2025Operating margin-158.4%
2016Net margin-3,645.2%
2017Net margin-2,884.3%
2018Net margin-4,875.5%
2019Net margin-3,694.6%
2020Net margin-4,822.5%
2021Net margin17.8%
2022Net marginNot reported
2023Net marginNot reported
2024Net margin-1,346.1%
2025Net margin-165.6%
2016Free cash flow margin-2,903.1%
2017Free cash flow margin-2,251.2%
2018Free cash flow margin-4,529.9%
2019Free cash flow marginNot reported
2020Free cash flow margin-4,697.4%
2021Free cash flow margin20.8%
2022Free cash flow marginNot reported
2023Free cash flow marginNot reported
2024Free cash flow margin-1,160.9%
2025Free cash flow margin-187.5%

Operating cash flow

Cash generated by the company’s normal business operations.

USD -323M 2025
Operating cash flow historyCash generated by the company’s normal business operations. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.57.3M-44.8M-146.9M-249.0M-351.1M201620212025
Values and sources
Operating cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Operating cash flow-35157000
2017Operating cash flow-47371000
2018Operating cash flow-68531000
2019Operating cash flow-50612000
2020Operating cash flow-71260000
2021Operating cash flow29131000
2022Operating cash flow-133675000
2023Operating cash flow-160601000
2024Operating cash flow-274903000
2025Operating cash flow-322980000

Free cash flow

Operating cash flow minus capital expenditure for the same period and unit.

USD -323.2M 2025
Free cash flow historyOperating cash flow minus capital expenditure for the same period and unit. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.57.2M-45.0M-147.1M-249.2M-351.3M201620212025
Values and sources
Free cash flow values and source evidence
PeriodSeriesValue(USD)Source evidence
2016Free cash flow-35418000
2017Free cash flow-47455000
2018Free cash flow-68718000
2019Free cash flowUnavailable
2020Free cash flow-71260000
2021Free cash flow29002000
2022Free cash flow-133675000
2023Free cash flow-160601000
2024Free cash flow-274903000
2025Free cash flow-323167000

Balance sheet

Liabilities and short-term ability to meet obligations at each period end.

Liabilities to assets

Total liabilities as a share of total assets.

87.8% 2025
Liabilities to assets historyTotal liabilities as a share of total assets. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.95%71%47%24%0%201620212025
Values and sources
Liabilities to assets values and source evidence
PeriodSeriesValueSource evidence
2016Liabilities / assets22.8%
2017Liabilities / assets24%
2018Liabilities / assets36.8%
2019Liabilities / assets50.3%
2020Liabilities / assets16.1%
2021Liabilities / assets9.2%
2022Liabilities / assets6%
2023Liabilities / assets9.6%
2024Liabilities / assets60.2%
2025Liabilities / assets87.8%

Current assets to current liabilities

Current assets divided by current liabilities.

4.4× 2025
Current assets to current liabilities historyCurrent assets divided by current liabilities. Values are shown by financial reporting period. Open Values and sources below for the exact observations and evidence.23.41×17.56×11.71×5.85×0.00×201620212025
Values and sources
Current assets to current liabilities values and source evidence
PeriodSeriesValueSource evidence
2016Current assets / current liabilities10.47×
2017Current assets / current liabilities8.45×
2018Current assets / current liabilities5.18×
2019Current assets / current liabilities3.39×
2020Current assets / current liabilities15.84×
2021Current assets / current liabilities21.68×
2022Current assets / current liabilities16.85×
2023Current assets / current liabilities10×
2024Current assets / current liabilities5.82×
2025Current assets / current liabilities4.4×

Cash generation

Compare reported profit with operating cash and capital spending. Free cash flow is calculated as operating cash flow minus capital expenditure when both exact, consolidated amounts match the same period and unit.

Cash generation by annual reporting period
PeriodNet incomeOperating cash flowCapital expenditureFree cash flow
2016 2016-01-01 – 2016-12-31
−USD 44.47 million
Exact value

Exact value: -44472000 USD

2016-01-01 – 2016-12-31: -44472000 USD Inspect Net Income Open source
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−USD 35.16 million
Exact value

Exact value: -35157000 USD

2016-01-01 – 2016-12-31: -35157000 USD Inspect Operating Cash Flow Open source
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USD 261,000
Exact value

Exact value: 261000 USD

2016-01-01 – 2016-12-31: 261000 USD Inspect Capital Expenditure Open source
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−USD 35.42 million
Calculation and evidence

-35157000 − 261000 USD

Exact free cash flow: -35418000 USD

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2017 2017-01-01 – 2017-12-31
−USD 60.8 million
Exact value

Exact value: -60802000 USD

2017-01-01 – 2017-12-31: -60802000 USD Inspect Net Income Open source
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−USD 47.37 million
Exact value

Exact value: -47371000 USD

2017-01-01 – 2017-12-31: -47371000 USD Inspect Operating Cash Flow Open source
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USD 84,000
Exact value

Exact value: 84000 USD

2017-01-01 – 2017-12-31: 84000 USD Inspect Capital Expenditure Open source
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−USD 47.46 million
Calculation and evidence

-47371000 − 84000 USD

Exact free cash flow: -47455000 USD

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2018 2018-01-01 – 2018-12-31
−USD 73.96 million
Exact value

Exact value: -73961000 USD

2018-01-01 – 2018-12-31: -73961000 USD Inspect Net Income Open source
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−USD 68.53 million
Exact value

Exact value: -68531000 USD

2018-01-01 – 2018-12-31: -68531000 USD Inspect Operating Cash Flow Open source
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USD 187,000
Exact value

Exact value: 187000 USD

2018-01-01 – 2018-12-31: 187000 USD Inspect Capital Expenditure Open source
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−USD 68.72 million
Calculation and evidence

-68531000 − 187000 USD

Exact free cash flow: -68718000 USD

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2019 2019-01-01 – 2019-12-31
−USD 56.05 million
Exact value

Exact value: -56047000 USD

2019-01-01 – 2019-12-31: -56047000 USD Inspect Net Income Open source
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−USD 50.61 million
Exact value

Exact value: -50612000 USD

2019-01-01 – 2019-12-31: -50612000 USD Inspect Operating Cash Flow Open source
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Unavailable Not reported for this period.
Unavailable

Free cash flow cannot be calculated because Capital expenditure is unavailable for this period.

2020 2020-01-01 – 2020-12-31
−USD 73.16 million
Exact value

Exact value: -73158000 USD

2020-01-01 – 2020-12-31: -73158000 USD Inspect Net Income Open source
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−USD 71.26 million
Exact value

Exact value: -71260000 USD

2020-01-01 – 2020-12-31: -71260000 USD Inspect Operating Cash Flow Open source
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USD 0
Exact value

Exact value: 0 USD

2020-01-01 – 2020-12-31: 0 USD Inspect Capital Expenditure Open source
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−USD 71.26 million
Calculation and evidence

-71260000 − 0 USD

Exact free cash flow: -71260000 USD

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2021 2021-01-01 – 2021-12-31
USD 24.93 million
Exact value

Exact value: 24926000 USD

2021-01-01 – 2021-12-31: 24926000 USD Inspect Net Income Open source
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USD 29.13 million
Exact value

Exact value: 29131000 USD

2021-01-01 – 2021-12-31: 29131000 USD Inspect Operating Cash Flow Open source
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USD 129,000
Exact value

Exact value: 129000 USD

2021-01-01 – 2021-12-31: 129000 USD Inspect Capital Expenditure Open source
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USD 29 million
Calculation and evidence

29131000 − 129000 USD

Exact free cash flow: 29002000 USD

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2022 2022-01-01 – 2022-12-31
−USD 149.34 million
Exact value

Exact value: -149338000 USD

2022-01-01 – 2022-12-31: -149338000 USD Inspect Net Income Open source
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−USD 133.68 million
Exact value

Exact value: -133675000 USD

2022-01-01 – 2022-12-31: -133675000 USD Inspect Operating Cash Flow Open source
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USD 0
Exact value

Exact value: 0 USD

2022-01-01 – 2022-12-31: 0 USD Inspect Capital Expenditure Open source
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−USD 133.68 million
Calculation and evidence

-133675000 − 0 USD

Exact free cash flow: -133675000 USD

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2023 2023-01-01 – 2023-12-31
−USD 209.36 million
Exact value

Exact value: -209360000 USD

2023-01-01 – 2023-12-31: -209360000 USD Inspect Net Income Open source
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−USD 160.6 million
Exact value

Exact value: -160601000 USD

2023-01-01 – 2023-12-31: -160601000 USD Inspect Operating Cash Flow Open source
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USD 0
Exact value

Exact value: 0 USD

2023-01-01 – 2023-12-31: 0 USD Inspect Capital Expenditure Open source
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−USD 160.6 million
Calculation and evidence

-160601000 − 0 USD

Exact free cash flow: -160601000 USD

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2024 2024-01-01 – 2024-12-31
−USD 318.76 million
Exact value

Exact value: -318758000 USD

2024-01-01 – 2024-12-31: -318758000 USD Inspect Net Income Open source
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−USD 274.9 million
Exact value

Exact value: -274903000 USD

2024-01-01 – 2024-12-31: -274903000 USD Inspect Operating Cash Flow Open source
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USD 0
Exact value

Exact value: 0 USD

2024-01-01 – 2024-12-31: 0 USD Inspect Capital Expenditure Open source
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−USD 274.9 million
Calculation and evidence

-274903000 − 0 USD

Exact free cash flow: -274903000 USD

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2025 2025-01-01 – 2025-12-31
−USD 285.42 million
Exact value

Exact value: -285422000 USD

2025-01-01 – 2025-12-31: -285422000 USD Inspect Net Income Open source
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−USD 322.98 million
Exact value

Exact value: -322980000 USD

2025-01-01 – 2025-12-31: -322980000 USD Inspect Operating Cash Flow Open source
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USD 187,000
Exact value

Exact value: 187000 USD

2025-01-01 – 2025-12-31: 187000 USD Inspect Capital Expenditure Open source
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−USD 323.17 million
Calculation and evidence

-322980000 − 187000 USD

Exact free cash flow: -323167000 USD

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Capital expenditure uses the canonical mapped positive-spending convention. A missing, ambiguous, incompatible, or negative-sign input is left blank. Values use the latest reported version.

Dataset coverage and company identifiers

Coverage reflects filings processed into this Fundies dataset; it does not imply every source filing is loaded.

59 filings · 2,728 latest values · 2,728 originally reported values

Dataset published . Source filing dates and reporting periods are shown separately.

Identifiers: 0001395937, 1395937, SNDX, edgar:1395937

Also known as SYNDAX PHARMACEUTICALS INC, SYNDAX PHARMACEUTICALS, INC., Syndax Pharmaceuticals Inc, Syndax Pharmaceuticals, Inc.