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Advanced Life Sciences Holdings, Inc.

EDGAR

Annual report (10-K) · filed 2011-03-24

30 filing records in this dataset, filed from 2005-11-10 to 2011-03-24. Explore the available filing history and original sources.

Inspect reported changes Compare with another company Historical disclosures Search filings Segments

Watchlist

Latest quarter

Revenue

-512 thousand USD

2010-12-31 · USD

Exact inputs and evidence

Revenue: 240830 USD Source
Revenue: 752853 USD Source

Operating margin

3,369.88%

2010-12-31 · %

Exact inputs and evidence

Operating Income: -22585012 USD Source
Operating Income: -5330435 USD Source
Revenue: 240830 USD Source
Revenue: 752853 USD Source

Operating cash flow

-1.05 million USD

2010-12-31 · USD

Exact inputs and evidence

Operating Cash Flow: -6431525 USD Source
Operating Cash Flow: -5385110 USD Source

Free cash flow

-1.05 million USD

2010-12-31 · USD

Exact inputs and evidence

Operating Cash Flow: -6431525 USD Source
Operating Cash Flow: -5385110 USD Source
Capital Expenditure: 0 USD Source
Capital Expenditure: 0 USD Source

Cash and cash equivalents: 160 thousand USD 2010-12-31 Source
Exact value

159596 USD
Long-term debt including current maturities: Not available
Shares outstanding: Not available

Trailing twelve months

The four most recent complete quarters added together. This gives a full-year view that includes the latest quarterly results.

Revenue

241 thousand USD

2010-01-01 – 2010-12-31

Exact inputs and evidence

Revenue: 479824 USD · 2010-01-01 – 2010-03-31 Source
Revenue: 273029 USD · 2010-04-01 – 2010-06-30 Source
Revenue: 0 USD · 2010-07-01 – 2010-09-30 Source
Revenue: 240830 USD · 2010-01-01 – 2010-12-31 Source
Revenue: 752853 USD · 2010-01-01 – 2010-09-30 Source

Net income

-22.8 million USD

2010-01-01 – 2010-12-31

Exact inputs and evidence

Net income: -1976763 USD · 2010-01-01 – 2010-03-31 Source
Net income: -2026921 USD · 2010-04-01 – 2010-06-30 Source
Net income: -2012429 USD · 2010-07-01 – 2010-09-30 Source
Net income: -22803869 USD · 2010-01-01 – 2010-12-31 Source
Net income: -6016114 USD · 2010-01-01 – 2010-09-30 Source

Operating cash flow

-6.43 million USD

2010-01-01 – 2010-12-31

Exact inputs and evidence

Operating cash flow: -2299798 USD · 2010-01-01 – 2010-03-31 Source
Operating cash flow: -3432759 USD · 2010-01-01 – 2010-06-30 Source
Operating cash flow: -2299798 USD · 2010-01-01 – 2010-03-31 Source
Operating cash flow: -5385110 USD · 2010-01-01 – 2010-09-30 Source
Operating cash flow: -3432759 USD · 2010-01-01 – 2010-06-30 Source
Operating cash flow: -6431525 USD · 2010-01-01 – 2010-12-31 Source
Operating cash flow: -5385110 USD · 2010-01-01 – 2010-09-30 Source

Capital expenditure

0 USD

2010-01-01 – 2010-12-31

Exact inputs and evidence

Capital expenditure: 0 USD · 2010-01-01 – 2010-03-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-06-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-03-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-09-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-06-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-12-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-09-30 Source

Free cash flow

-6.43 million USD

2010-01-01 – 2010-12-31

Exact inputs and evidence

Operating cash flow: -2299798 USD · 2010-01-01 – 2010-03-31 Source
Operating cash flow: -3432759 USD · 2010-01-01 – 2010-06-30 Source
Operating cash flow: -2299798 USD · 2010-01-01 – 2010-03-31 Source
Operating cash flow: -5385110 USD · 2010-01-01 – 2010-09-30 Source
Operating cash flow: -3432759 USD · 2010-01-01 – 2010-06-30 Source
Operating cash flow: -6431525 USD · 2010-01-01 – 2010-12-31 Source
Operating cash flow: -5385110 USD · 2010-01-01 – 2010-09-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-03-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-06-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-03-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-09-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-06-30 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-12-31 Source
Capital expenditure: 0 USD · 2010-01-01 – 2010-09-30 Source

Includes later revisions to earlier periods. Annual charts exclude incomplete years.

Latest filing recorded: 2011-03-24.

Financial data available through: 2010-12-31.

Coverage by financial measure

Revenue: 8 of 11 periods available· newest 2010-12-31
Operating income: 8 of 11 periods available· newest 2010-12-31
Net income: 8 of 11 periods available· newest 2010-12-31
Operating cash flow: 8 of 11 periods available· newest 2010-12-31
Capital expenditure: 8 of 11 periods available· newest 2010-12-31
Total assets: 7 of 11 periods available· newest 2010-12-31
Total liabilities: 7 of 11 periods available· newest 2010-12-31
Current assets: 7 of 11 periods available· newest 2010-12-31
Current liabilities: 7 of 11 periods available· newest 2010-12-31
Cash and cash equivalents: 8 of 11 periods available· newest 2010-12-31
long term debt: No compatible figures in this window
shares outstanding: No compatible figures in this window

Coverage describes values retained in this snapshot. Missing values are not zero; loading limits are reported separately.

What changed year over year

Latest complete year compared with the corresponding period one year earlier. These are measured changes; they do not establish their business causes.

Revenue
+USD 240,830

Prior period

USD 0

2009-01-01 – 2009-12-31
Current period

USD 240,830

2010-01-01 – 2010-12-31

Exact inputs and evidence

240830 − 0 = 240830 USD

0 USD · 2009-01-01 – 2009-12-31
Inspect prior input Prior source
240830 USD · 2010-01-01 – 2010-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Revenue · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Year-over-year change in Revenue: 240830 USD Concept: fundies:Revenue Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:Revenue: 240830 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#5625 Input fundies:Revenue: 0 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#5297
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Net income
+USD 9.52 million

Prior period

−USD 32.32 million

2009-01-01 – 2009-12-31
Current period

−USD 22.8 million

2010-01-01 – 2010-12-31

Exact inputs and evidence

-22803869 − -32324413 = 9520544 USD

-32324413 USD · 2009-01-01 – 2009-12-31
Inspect prior input Prior source
-22803869 USD · 2010-01-01 – 2010-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Net income · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Year-over-year change in Net income: 9520544 USD Concept: fundies:NetIncome Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:NetIncome: -22803869 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#5977 Input fundies:NetIncome: -32324413 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#5632
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Operating cash flow
+USD 5.51 million

Prior period

−USD 11.94 million

2009-01-01 – 2009-12-31
Current period

−USD 6.43 million

2010-01-01 – 2010-12-31

Exact inputs and evidence

-6431525 − -11936727 = 5505202 USD

-11936727 USD · 2009-01-01 – 2009-12-31
Inspect prior input Prior source
-6431525 USD · 2010-01-01 – 2010-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Operating cash flow · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Year-over-year change in Operating cash flow: 5505202 USD Concept: fundies:OperatingCashFlow Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:OperatingCashFlow: -6431525 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 Input fundies:OperatingCashFlow: -11936727 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765
The citation records this snapshot. The page link may show a newer release later.
Capital expenditure
-100%

Prior period

USD 5,466

2009-01-01 – 2009-12-31
Current period

USD 0

2010-01-01 – 2010-12-31

Exact inputs and evidence

0 − 5466 = -5466 USD

5466 USD · 2009-01-01 – 2009-12-31
Inspect prior input Prior source
0 USD · 2010-01-01 – 2010-12-31
Inspect current input Current source

Share or cite

Citation for Year-over-year change in Capital expenditure · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Year-over-year change in Capital expenditure: -5466 USD Concept: fundies:CapitalExpenditure Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#period-changes-title Computed: Current period minus corresponding prior-year period Input fundies:CapitalExpenditure: 0 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 Input fundies:CapitalExpenditure: 5466 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813
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Where revenue goes

How a period’s revenue divides into costs and what remains as profit. Items marked Derived are calculated by subtraction from reported figures.

2010 2010-01-01 – 2010-12-31

Revenue USD 240,830 100% of revenue
Operating costs Derived USD 22.83 million 9,478% of revenue
Operating income −USD 22.59 million −9,378% of revenue
Tax, interest and other Derived USD 218,857 91% of revenue
Net income −USD 22.8 million −9,469% of revenue

Cash

Operating cash flow −USD 6.43 million −2,671% of revenue
Capital expenditure USD 0 0% of revenue
Free cash flow Derived −USD 6.43 million −2,671% of revenue

Share of revenue by period

Net income
Tax, interest and other
Operating costs

2003 Operating loss: operating costs were 1,419% of revenue.
2004 Operating loss: operating costs were 8,541% of revenue.
2005 Operating loss: operating costs were 5,236% of revenue.
2006 Operating loss: operating costs were 56,951% of revenue.
2007 Operating loss: operating costs were 5,236% of revenue.
2008 Operating loss: operating costs were 56,951% of revenue.
2009 Not shown: operating income or net income is not reported.
2010 Operating loss: operating costs were 9,478% of revenue.

Values and sources

Revenue breakdown by annual reporting period
Period	Revenue	Operating costs	Operating income	Tax, interest and other	Net income	Free cash flow	Source
2003 2003-01-01 – 2003-12-31	180427	2560977 Derived	-2380550	170938 Derived	-2551488	-2295264 Derived	Source 2003-01-01 – 2003-12-31: 180427 USD Inspect Revenue Open source 2003-01-01 – 2003-12-31: -2380550 USD Inspect Operating Income Open source 2003-01-01 – 2003-12-31: -2551488 USD Inspect Net Income Open source 2003-01-01 – 2003-12-31: -2189855 USD Inspect Operating Cash Flow Open source 2003-01-01 – 2003-12-31: 105409 USD Inspect Capital Expenditure Open source
2004 2004-01-01 – 2004-12-31	319780	27311821 Derived	-26992041	194877 Derived	-27186918	-2401852 Derived	Source 2004-01-01 – 2004-12-31: 319780 USD Inspect Revenue Open source 2004-01-01 – 2004-12-31: -26992041 USD Inspect Operating Income Open source 2004-01-01 – 2004-12-31: -27186918 USD Inspect Net Income Open source 2004-01-01 – 2004-12-31: -2311075 USD Inspect Operating Cash Flow Open source 2004-01-01 – 2004-12-31: 90777 USD Inspect Capital Expenditure Open source
2005 2005-01-01 – 2005-12-31	121451	6359613 Derived	-6238162	206084 Derived	-6444246	-16360209 Derived	Source 2005-01-01 – 2005-12-31: 121451 USD Inspect Revenue Open source 2005-01-01 – 2005-12-31: -6238162 USD Inspect Operating Income Open source 2005-01-01 – 2005-12-31: -6444246 USD Inspect Net Income Open source 2005-01-01 – 2005-12-31: -16272557 USD Inspect Operating Cash Flow Open source 2005-01-01 – 2005-12-31: 87652 USD Inspect Capital Expenditure Open source
2006 2006-01-01 – 2006-12-31	39788	22659508 Derived	-22619720	-2079084 Derived	-20540636	-22469810 Derived	Source 2006-01-01 – 2006-12-31: 39788 USD Inspect Revenue Open source 2006-01-01 – 2006-12-31: -22619720 USD Inspect Operating Income Open source 2006-01-01 – 2006-12-31: -20540636 USD Inspect Net Income Open source 2006-01-01 – 2006-12-31: -22181783 USD Inspect Operating Cash Flow Open source 2006-01-01 – 2006-12-31: 288027 USD Inspect Capital Expenditure Open source
2007 2007-01-01 – 2007-12-31	121451	6359613 Derived	-6238162	26086251 Derived	-32324413	-26567346 Derived	Source 2007-01-01 – 2007-12-31: 121451 USD Inspect Revenue Open source 2007-01-01 – 2007-12-31: -6238162 USD Inspect Operating Income Open source 2007-01-01 – 2007-12-31: -32324413 USD Inspect Net Income Open source 2007-01-01 – 2007-12-31: -26508910 USD Inspect Operating Cash Flow Open source 2007-01-01 – 2007-12-31: 58436 USD Inspect Capital Expenditure Open source
2008 2008-01-01 – 2008-12-31	39788	22659508 Derived	-22619720	184149 Derived	-22803869	-24424419 Derived	Source 2008-01-01 – 2008-12-31: 39788 USD Inspect Revenue Open source 2008-01-01 – 2008-12-31: -22619720 USD Inspect Operating Income Open source 2008-01-01 – 2008-12-31: -22803869 USD Inspect Net Income Open source 2008-01-01 – 2008-12-31: -24062066 USD Inspect Operating Cash Flow Open source 2008-01-01 – 2008-12-31: 362353 USD Inspect Capital Expenditure Open source
2009 2009-01-01 – 2009-12-31	0	32575334 Derived	-32575334	-250921 Derived	-32324413	-11942193 Derived	Source 2009-01-01 – 2009-12-31: 0 USD Inspect Revenue Open source 2009-01-01 – 2009-12-31: -32575334 USD Inspect Operating Income Open source 2009-01-01 – 2009-12-31: -32324413 USD Inspect Net Income Open source 2009-01-01 – 2009-12-31: -11936727 USD Inspect Operating Cash Flow Open source 2009-01-01 – 2009-12-31: 5466 USD Inspect Capital Expenditure Open source
2010 2010-01-01 – 2010-12-31	240830	22825842 Derived	-22585012	218857 Derived	-22803869	-6431525 Derived	Source 2010-01-01 – 2010-12-31: 240830 USD Inspect Revenue Open source 2010-01-01 – 2010-12-31: -22585012 USD Inspect Operating Income Open source 2010-01-01 – 2010-12-31: -22803869 USD Inspect Net Income Open source 2010-01-01 – 2010-12-31: -6431525 USD Inspect Operating Cash Flow Open source 2010-01-01 – 2010-12-31: 0 USD Inspect Capital Expenditure Open source

Amounts are exact, in USD.

Growth

Sales over time and how quickly they are changing.

Revenue

Revenue reported for each complete financial period.

USD 240.8K 2010

Values and sources

Revenue values and source evidence
Period	Series	Value(USD)	Source evidence
20032003-12-31	Revenue	180427	Revenue: 180427 Open source
20042004-12-31	Revenue	319780	Revenue: 319780 Open source
20052005-12-31	Revenue	121451	Revenue: 121451 Open source
20062006-12-31	Revenue	39788	Revenue: 39788 Open source
20072007-12-31	Revenue	121451	Revenue: 121451 Open source
20082008-12-31	Revenue	39788	Revenue: 39788 Open source
20092009-12-31	Revenue	0	Revenue: 0 Open source
20102010-12-31	Revenue	240830	Revenue: 240830 Open source

Revenue growth

Change in revenue from the same financial period one year earlier.

-100% 2009

Values and sources

Revenue growth values and source evidence
Period	Series	Value	Source evidence
20032003-12-31	Year over year	No prior comparable period	Revenue: 180427 Open source
20042004-12-31	Year over year	77.2%	Revenue: 319780 Open source Revenue: 180427 Open source
20052005-12-31	Year over year	-62%	Revenue: 121451 Open source Revenue: 319780 Open source
20062006-12-31	Year over year	-67.2%	Revenue: 39788 Open source Revenue: 121451 Open source
20072007-12-31	Year over year	205.2%	Revenue: 121451 Open source Revenue: 39788 Open source
20082008-12-31	Year over year	-67.2%	Revenue: 39788 Open source Revenue: 121451 Open source
20092009-12-31	Year over year	-100%	Revenue: 0 Open source Revenue: 39788 Open source
20102010-12-31	Year over year	No prior comparable period	Revenue: 240830 Open source Revenue: 0 Open source

Profit and cash

How much revenue becomes profit, and how much cash operations generate.

Profit margins

Operating income, net income and free cash flow as a share of revenue.

Operating margin -9,378% 2010

Net margin -9,468.9% 2010

Free cash flow margin -2,670.6% 2010

Operating margin
Net margin
Free cash flow margin

Values and sources

Profit margins values and source evidence
Period	Series	Value	Source evidence
20032003-12-31	Operating margin	-1,319.4%	Operating Income: -2380550 Open source Revenue: 180427 Open source
20042004-12-31	Operating margin	-8,440.8%	Operating Income: -26992041 Open source Revenue: 319780 Open source
20052005-12-31	Operating margin	-5,136.4%	Operating Income: -6238162 Open source Revenue: 121451 Open source
20062006-12-31	Operating margin	-56,850.6%	Operating Income: -22619720 Open source Revenue: 39788 Open source
20072007-12-31	Operating margin	-5,136.4%	Operating Income: -6238162 Open source Revenue: 121451 Open source
20082008-12-31	Operating margin	-56,850.6%	Operating Income: -22619720 Open source Revenue: 39788 Open source
20092009-12-31	Operating margin	Not reported	Operating Income: -32575334 Open source Revenue: 0 Open source
20102010-12-31	Operating margin	-9,378%	Operating Income: -22585012 Open source Revenue: 240830 Open source
20032003-12-31	Net margin	-1,414.1%	Net Income: -2551488 Open source Revenue: 180427 Open source
20042004-12-31	Net margin	-8,501.8%	Net Income: -27186918 Open source Revenue: 319780 Open source
20052005-12-31	Net margin	-5,306%	Net Income: -6444246 Open source Revenue: 121451 Open source
20062006-12-31	Net margin	-51,625.2%	Net Income: -20540636 Open source Revenue: 39788 Open source
20072007-12-31	Net margin	-26,615.2%	Net Income: -32324413 Open source Revenue: 121451 Open source
20082008-12-31	Net margin	-57,313.4%	Net Income: -22803869 Open source Revenue: 39788 Open source
20092009-12-31	Net margin	Not reported	Net Income: -32324413 Open source Revenue: 0 Open source
20102010-12-31	Net margin	-9,468.9%	Net Income: -22803869 Open source Revenue: 240830 Open source
20032003-12-31	Free cash flow margin	-1,272.1%	Revenue: 180427 Open source Operating Cash Flow: -2189855 Open source Capital Expenditure: 105409 Open source
20042004-12-31	Free cash flow margin	-751.1%	Revenue: 319780 Open source Operating Cash Flow: -2311075 Open source Capital Expenditure: 90777 Open source
20052005-12-31	Free cash flow margin	-13,470.6%	Revenue: 121451 Open source Operating Cash Flow: -16272557 Open source Capital Expenditure: 87652 Open source
20062006-12-31	Free cash flow margin	-56,473.8%	Revenue: 39788 Open source Operating Cash Flow: -22181783 Open source Capital Expenditure: 288027 Open source
20072007-12-31	Free cash flow margin	-21,875%	Revenue: 121451 Open source Operating Cash Flow: -26508910 Open source Capital Expenditure: 58436 Open source
20082008-12-31	Free cash flow margin	-61,386.4%	Revenue: 39788 Open source Operating Cash Flow: -24062066 Open source Capital Expenditure: 362353 Open source
20092009-12-31	Free cash flow margin	Not reported	Revenue: 0 Open source Operating Cash Flow: -11936727 Open source Capital Expenditure: 5466 Open source
20102010-12-31	Free cash flow margin	-2,670.6%	Revenue: 240830 Open source Operating Cash Flow: -6431525 Open source Capital Expenditure: 0 Open source

Operating cash flow

Cash generated by the company’s normal business operations.

USD -6.4M 2010

Values and sources

Operating cash flow values and source evidence
Period	Series	Value(USD)	Source evidence
20032003-12-31	Operating cash flow	-2189855	Operating Cash Flow: -2189855 Open source
20042004-12-31	Operating cash flow	-2311075	Operating Cash Flow: -2311075 Open source
20052005-12-31	Operating cash flow	-16272557	Operating Cash Flow: -16272557 Open source
20062006-12-31	Operating cash flow	-22181783	Operating Cash Flow: -22181783 Open source
20072007-12-31	Operating cash flow	-26508910	Operating Cash Flow: -26508910 Open source
20082008-12-31	Operating cash flow	-24062066	Operating Cash Flow: -24062066 Open source
20092009-12-31	Operating cash flow	-11936727	Operating Cash Flow: -11936727 Open source
20102010-12-31	Operating cash flow	-6431525	Operating Cash Flow: -6431525 Open source

Free cash flow

Operating cash flow minus capital expenditure for the same period and unit.

USD -6.4M 2010

Values and sources

Free cash flow values and source evidence
Period	Series	Value(USD)	Source evidence
20032003-12-31	Free cash flow	-2295264	Operating Cash Flow: -2189855 Open source Capital Expenditure: 105409 Open source
20042004-12-31	Free cash flow	-2401852	Operating Cash Flow: -2311075 Open source Capital Expenditure: 90777 Open source
20052005-12-31	Free cash flow	-16360209	Operating Cash Flow: -16272557 Open source Capital Expenditure: 87652 Open source
20062006-12-31	Free cash flow	-22469810	Operating Cash Flow: -22181783 Open source Capital Expenditure: 288027 Open source
20072007-12-31	Free cash flow	-26567346	Operating Cash Flow: -26508910 Open source Capital Expenditure: 58436 Open source
20082008-12-31	Free cash flow	-24424419	Operating Cash Flow: -24062066 Open source Capital Expenditure: 362353 Open source
20092009-12-31	Free cash flow	-11942193	Operating Cash Flow: -11936727 Open source Capital Expenditure: 5466 Open source
20102010-12-31	Free cash flow	-6431525	Operating Cash Flow: -6431525 Open source Capital Expenditure: 0 Open source

Balance sheet

Liabilities and short-term ability to meet obligations at each period end.

Liabilities to assets

Total liabilities as a share of total assets.

1,358.4% 2010

Values and sources

Liabilities to assets values and source evidence
Period	Series	Value	Source evidence
2003-12-31	Liabilities / assets	Not reported	No source recorded
20042004-12-31	Liabilities / assets	1,898.7%	Total Liabilities: 19289733 Open source Total Assets: 1015932 Open source
20052005-12-31	Liabilities / assets	48.2%	Total Liabilities: 7726173 Open source Total Assets: 16021910 Open source
20062006-12-31	Liabilities / assets	29.9%	Total Liabilities: 9115174 Open source Total Assets: 30509679 Open source
20072007-12-31	Liabilities / assets	61.5%	Total Liabilities: 12250568 Open source Total Assets: 19911542 Open source
20082008-12-31	Liabilities / assets	538.9%	Total Liabilities: 15197594 Open source Total Assets: 2820053 Open source
20092009-12-31	Liabilities / assets	225.7%	Total Liabilities: 14507818 Open source Total Assets: 6427771 Open source
20102010-12-31	Liabilities / assets	1,358.4%	Total Liabilities: 10494615 Open source Total Assets: 772593 Open source

Current assets to current liabilities

Current assets divided by current liabilities.

0.02× 2010

Values and sources

Current assets to current liabilities values and source evidence
Period	Series	Value	Source evidence
2003-12-31	Current assets / current liabilities	Not reported	No source recorded
20042004-12-31	Current assets / current liabilities	0.05×	Current Assets: 778562 Open source Current Liabilities: 16695851 Open source
20052005-12-31	Current assets / current liabilities	28.31×	Current Assets: 15711596 Open source Current Liabilities: 555025 Open source
20062006-12-31	Current assets / current liabilities	5.82×	Current Assets: 30073114 Open source Current Liabilities: 5168072 Open source
20072007-12-31	Current assets / current liabilities	3.37×	Current Assets: 19643011 Open source Current Liabilities: 5822750 Open source
20082008-12-31	Current assets / current liabilities	0.71×	Current Assets: 1961673 Open source Current Liabilities: 2778244 Open source
20092009-12-31	Current assets / current liabilities	1.78×	Current Assets: 3572316 Open source Current Liabilities: 2007818 Open source
20102010-12-31	Current assets / current liabilities	0.02×	Current Assets: 204784 Open source Current Liabilities: 10478604 Open source

Cash generation

Compare reported profit with operating cash and capital spending. Free cash flow is calculated as operating cash flow minus capital expenditure when both exact, consolidated amounts match the same period and unit.

Cash generation by annual reporting period
Period	Net income	Operating cash flow	Capital expenditure	Free cash flow
2003 2003-01-01 – 2003-12-31	−USD 2.55 million Exact value Exact value: -2551488 USD 2003-01-01 – 2003-12-31: -2551488 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2003-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -2551488 USD Concept: fundies:NetIncome Period: 2003-01-01 to 2003-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2003-12-31&surface=latest&period_type=duration&start=2003-01-01&unit=USD&dimensions= Input fundies:NetIncome: -2551488 USD (2003-01-01 to 2003-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#10281 The citation records this snapshot. The page link may show a newer release later.	−USD 2.19 million Exact value Exact value: -2189855 USD 2003-01-01 – 2003-12-31: -2189855 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2003-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -2189855 USD Concept: fundies:OperatingCashFlow Period: 2003-01-01 to 2003-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2003-12-31&surface=latest&period_type=duration&start=2003-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -2189855 USD (2003-01-01 to 2003-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#10941 The citation records this snapshot. The page link may show a newer release later.	USD 105,409 Exact value Exact value: 105409 USD 2003-01-01 – 2003-12-31: 105409 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2003-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 105409 USD Concept: fundies:CapitalExpenditure Period: 2003-01-01 to 2003-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2003-12-31&surface=latest&period_type=duration&start=2003-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 105409 USD (2003-01-01 to 2003-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#11018 The citation records this snapshot. The page link may show a newer release later.	−USD 2.3 million Calculation and evidence -2189855 − 105409 USD Exact free cash flow: -2295264 USD 2003-01-01 – 2003-12-31: -2189855 USD · Inspect Operating Cash Flow · Source 2003-01-01 – 2003-12-31: 105409 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2003-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -2295264 USD Concept: free-cash-flow Period: 2003-01-01 to 2003-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -2189855 USD (2003-01-01 to 2003-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#10941 Input fundies:CapitalExpenditure: 105409 USD (2003-01-01 to 2003-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#11018 The citation records this snapshot. The page link may show a newer release later.
2004 2004-01-01 – 2004-12-31	−USD 27.19 million Exact value Exact value: -27186918 USD 2004-01-01 – 2004-12-31: -27186918 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2004-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -27186918 USD Concept: fundies:NetIncome Period: 2004-01-01 to 2004-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2004-12-31&surface=latest&period_type=duration&start=2004-01-01&unit=USD&dimensions= Input fundies:NetIncome: -27186918 USD (2004-01-01 to 2004-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-07-037565.txt#7840 The citation records this snapshot. The page link may show a newer release later.	−USD 2.31 million Exact value Exact value: -2311075 USD 2004-01-01 – 2004-12-31: -2311075 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2004-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -2311075 USD Concept: fundies:OperatingCashFlow Period: 2004-01-01 to 2004-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2004-12-31&surface=latest&period_type=duration&start=2004-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -2311075 USD (2004-01-01 to 2004-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#10941 The citation records this snapshot. The page link may show a newer release later.	USD 90,777 Exact value Exact value: 90777 USD 2004-01-01 – 2004-12-31: 90777 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2004-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 90777 USD Concept: fundies:CapitalExpenditure Period: 2004-01-01 to 2004-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2004-12-31&surface=latest&period_type=duration&start=2004-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 90777 USD (2004-01-01 to 2004-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#11018 The citation records this snapshot. The page link may show a newer release later.	−USD 2.4 million Calculation and evidence -2311075 − 90777 USD Exact free cash flow: -2401852 USD 2004-01-01 – 2004-12-31: -2311075 USD · Inspect Operating Cash Flow · Source 2004-01-01 – 2004-12-31: 90777 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2004-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -2401852 USD Concept: free-cash-flow Period: 2004-01-01 to 2004-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -2311075 USD (2004-01-01 to 2004-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#10941 Input fundies:CapitalExpenditure: 90777 USD (2004-01-01 to 2004-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001104659-06-016906.txt#11018 The citation records this snapshot. The page link may show a newer release later.
2005 2005-01-01 – 2005-12-31	−USD 6.44 million Exact value Exact value: -6444246 USD 2005-01-01 – 2005-12-31: -6444246 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2005-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -6444246 USD Concept: fundies:NetIncome Period: 2005-01-01 to 2005-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2005-12-31&surface=latest&period_type=duration&start=2005-01-01&unit=USD&dimensions= Input fundies:NetIncome: -6444246 USD (2005-01-01 to 2005-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-08-004069.txt#5372 The citation records this snapshot. The page link may show a newer release later.	−USD 16.27 million Exact value Exact value: -16272557 USD 2005-01-01 – 2005-12-31: -16272557 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2005-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -16272557 USD Concept: fundies:OperatingCashFlow Period: 2005-01-01 to 2005-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2005-12-31&surface=latest&period_type=duration&start=2005-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -16272557 USD (2005-01-01 to 2005-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-08-004069.txt#5714 The citation records this snapshot. The page link may show a newer release later.	USD 87,652 Exact value Exact value: 87652 USD 2005-01-01 – 2005-12-31: 87652 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2005-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 87652 USD Concept: fundies:CapitalExpenditure Period: 2005-01-01 to 2005-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2005-12-31&surface=latest&period_type=duration&start=2005-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 87652 USD (2005-01-01 to 2005-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-08-004069.txt#5767 The citation records this snapshot. The page link may show a newer release later.	−USD 16.36 million Calculation and evidence -16272557 − 87652 USD Exact free cash flow: -16360209 USD 2005-01-01 – 2005-12-31: -16272557 USD · Inspect Operating Cash Flow · Source 2005-01-01 – 2005-12-31: 87652 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2005-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -16360209 USD Concept: free-cash-flow Period: 2005-01-01 to 2005-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -16272557 USD (2005-01-01 to 2005-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-08-004069.txt#5714 Input fundies:CapitalExpenditure: 87652 USD (2005-01-01 to 2005-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-08-004069.txt#5767 The citation records this snapshot. The page link may show a newer release later.
2006 2006-01-01 – 2006-12-31	−USD 20.54 million Exact value Exact value: -20540636 USD 2006-01-01 – 2006-12-31: -20540636 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2006-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -20540636 USD Concept: fundies:NetIncome Period: 2006-01-01 to 2006-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2006-12-31&surface=latest&period_type=duration&start=2006-01-01&unit=USD&dimensions= Input fundies:NetIncome: -20540636 USD (2006-01-01 to 2006-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6566 The citation records this snapshot. The page link may show a newer release later.	−USD 22.18 million Exact value Exact value: -22181783 USD 2006-01-01 – 2006-12-31: -22181783 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2006-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -22181783 USD Concept: fundies:OperatingCashFlow Period: 2006-01-01 to 2006-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2006-12-31&surface=latest&period_type=duration&start=2006-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -22181783 USD (2006-01-01 to 2006-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6908 The citation records this snapshot. The page link may show a newer release later.	USD 288,027 Exact value Exact value: 288027 USD 2006-01-01 – 2006-12-31: 288027 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2006-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 288027 USD Concept: fundies:CapitalExpenditure Period: 2006-01-01 to 2006-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2006-12-31&surface=latest&period_type=duration&start=2006-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 288027 USD (2006-01-01 to 2006-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6956 The citation records this snapshot. The page link may show a newer release later.	−USD 22.47 million Calculation and evidence -22181783 − 288027 USD Exact free cash flow: -22469810 USD 2006-01-01 – 2006-12-31: -22181783 USD · Inspect Operating Cash Flow · Source 2006-01-01 – 2006-12-31: 288027 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2006-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -22469810 USD Concept: free-cash-flow Period: 2006-01-01 to 2006-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -22181783 USD (2006-01-01 to 2006-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6908 Input fundies:CapitalExpenditure: 288027 USD (2006-01-01 to 2006-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6956 The citation records this snapshot. The page link may show a newer release later.
2007 2007-01-01 – 2007-12-31	−USD 32.32 million Exact value Exact value: -32324413 USD 2007-01-01 – 2007-12-31: -32324413 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2007-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -32324413 USD Concept: fundies:NetIncome Period: 2007-01-01 to 2007-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2007-12-31&surface=latest&period_type=duration&start=2007-01-01&unit=USD&dimensions= Input fundies:NetIncome: -32324413 USD (2007-01-01 to 2007-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6566 The citation records this snapshot. The page link may show a newer release later.	−USD 26.51 million Exact value Exact value: -26508910 USD 2007-01-01 – 2007-12-31: -26508910 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2007-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -26508910 USD Concept: fundies:OperatingCashFlow Period: 2007-01-01 to 2007-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2007-12-31&surface=latest&period_type=duration&start=2007-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -26508910 USD (2007-01-01 to 2007-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#7393 The citation records this snapshot. The page link may show a newer release later.	USD 58,436 Exact value Exact value: 58436 USD 2007-01-01 – 2007-12-31: 58436 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2007-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 58436 USD Concept: fundies:CapitalExpenditure Period: 2007-01-01 to 2007-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2007-12-31&surface=latest&period_type=duration&start=2007-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 58436 USD (2007-01-01 to 2007-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#7441 The citation records this snapshot. The page link may show a newer release later.	−USD 26.57 million Calculation and evidence -26508910 − 58436 USD Exact free cash flow: -26567346 USD 2007-01-01 – 2007-12-31: -26508910 USD · Inspect Operating Cash Flow · Source 2007-01-01 – 2007-12-31: 58436 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2007-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -26567346 USD Concept: free-cash-flow Period: 2007-01-01 to 2007-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -26508910 USD (2007-01-01 to 2007-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#7393 Input fundies:CapitalExpenditure: 58436 USD (2007-01-01 to 2007-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#7441 The citation records this snapshot. The page link may show a newer release later.
2008 2008-01-01 – 2008-12-31	−USD 22.8 million Exact value Exact value: -22803869 USD 2008-01-01 – 2008-12-31: -22803869 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2008-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -22803869 USD Concept: fundies:NetIncome Period: 2008-01-01 to 2008-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2008-12-31&surface=latest&period_type=duration&start=2008-01-01&unit=USD&dimensions= Input fundies:NetIncome: -22803869 USD (2008-01-01 to 2008-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-09-001072.txt#6566 The citation records this snapshot. The page link may show a newer release later.	−USD 24.06 million Exact value Exact value: -24062066 USD 2008-01-01 – 2008-12-31: -24062066 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2008-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -24062066 USD Concept: fundies:OperatingCashFlow Period: 2008-01-01 to 2008-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2008-12-31&surface=latest&period_type=duration&start=2008-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -24062066 USD (2008-01-01 to 2008-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 The citation records this snapshot. The page link may show a newer release later.	USD 362,353 Exact value Exact value: 362353 USD 2008-01-01 – 2008-12-31: 362353 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2008-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 362353 USD Concept: fundies:CapitalExpenditure Period: 2008-01-01 to 2008-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2008-12-31&surface=latest&period_type=duration&start=2008-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 362353 USD (2008-01-01 to 2008-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.	−USD 24.42 million Calculation and evidence -24062066 − 362353 USD Exact free cash flow: -24424419 USD 2008-01-01 – 2008-12-31: -24062066 USD · Inspect Operating Cash Flow · Source 2008-01-01 – 2008-12-31: 362353 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2008-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -24424419 USD Concept: free-cash-flow Period: 2008-01-01 to 2008-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -24062066 USD (2008-01-01 to 2008-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 Input fundies:CapitalExpenditure: 362353 USD (2008-01-01 to 2008-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.
2009 2009-01-01 – 2009-12-31	−USD 32.32 million Exact value Exact value: -32324413 USD 2009-01-01 – 2009-12-31: -32324413 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2009-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -32324413 USD Concept: fundies:NetIncome Period: 2009-01-01 to 2009-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2009-12-31&surface=latest&period_type=duration&start=2009-01-01&unit=USD&dimensions= Input fundies:NetIncome: -32324413 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-10-002015.txt#5632 The citation records this snapshot. The page link may show a newer release later.	−USD 11.94 million Exact value Exact value: -11936727 USD 2009-01-01 – 2009-12-31: -11936727 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2009-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -11936727 USD Concept: fundies:OperatingCashFlow Period: 2009-01-01 to 2009-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2009-12-31&surface=latest&period_type=duration&start=2009-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -11936727 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 The citation records this snapshot. The page link may show a newer release later.	USD 5,466 Exact value Exact value: 5466 USD 2009-01-01 – 2009-12-31: 5466 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2009-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 5466 USD Concept: fundies:CapitalExpenditure Period: 2009-01-01 to 2009-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2009-12-31&surface=latest&period_type=duration&start=2009-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 5466 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.	−USD 11.94 million Calculation and evidence -11936727 − 5466 USD Exact free cash flow: -11942193 USD 2009-01-01 – 2009-12-31: -11936727 USD · Inspect Operating Cash Flow · Source 2009-01-01 – 2009-12-31: 5466 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2009-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -11942193 USD Concept: free-cash-flow Period: 2009-01-01 to 2009-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -11936727 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 Input fundies:CapitalExpenditure: 5466 USD (2009-01-01 to 2009-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.
2010 2010-01-01 – 2010-12-31	−USD 22.8 million Exact value Exact value: -22803869 USD 2010-01-01 – 2010-12-31: -22803869 USD Inspect Net Income Open source Share or cite Citation for Net Income · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Net Income: -22803869 USD Concept: fundies:NetIncome Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ANetIncome&period=2010-12-31&surface=latest&period_type=duration&start=2010-01-01&unit=USD&dimensions= Input fundies:NetIncome: -22803869 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#5977 The citation records this snapshot. The page link may show a newer release later.	−USD 6.43 million Exact value Exact value: -6431525 USD 2010-01-01 – 2010-12-31: -6431525 USD Inspect Operating Cash Flow Open source Share or cite Citation for Operating Cash Flow · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Operating Cash Flow: -6431525 USD Concept: fundies:OperatingCashFlow Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3AOperatingCashFlow&period=2010-12-31&surface=latest&period_type=duration&start=2010-01-01&unit=USD&dimensions= Input fundies:OperatingCashFlow: -6431525 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 The citation records this snapshot. The page link may show a newer release later.	USD 0 Exact value Exact value: 0 USD 2010-01-01 – 2010-12-31: 0 USD Inspect Capital Expenditure Open source Share or cite Citation for Capital Expenditure · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Capital Expenditure: 0 USD Concept: fundies:CapitalExpenditure Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734/explain?concept=fundies%3ACapitalExpenditure&period=2010-12-31&surface=latest&period_type=duration&start=2010-01-01&unit=USD&dimensions= Input fundies:CapitalExpenditure: 0 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.	−USD 6.43 million Calculation and evidence -6431525 − 0 USD Exact free cash flow: -6431525 USD 2010-01-01 – 2010-12-31: -6431525 USD · Inspect Operating Cash Flow · Source 2010-01-01 – 2010-12-31: 0 USD · Inspect Capital Expenditure · Source Share or cite Citation for Free cash flow · Advanced Life Sciences Holdings, Inc. · 2010-12-31 Advanced Life Sciences Holdings, Inc. (edgar:1322734) Free cash flow: -6431525 USD Concept: free-cash-flow Period: 2010-01-01 to 2010-12-31 Values: Latest reported Published: 2026-11-02T15:31:57Z Snapshot: 4c34d93c8cae04b459e43993884a99ac33d39a3060564a067ed9999bf20eff36 Dimensions: Consolidated View: https://fundies.io/companies/edgar/1322734?view=overview&cadence=annual&surface=latest#cash-generation-title Computed: Operating cash flow minus capital expenditure Input fundies:OperatingCashFlow: -6431525 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7765 Input fundies:CapitalExpenditure: 0 USD (2010-01-01 to 2010-12-31) Dimensions: Consolidated Source: https://www.sec.gov/Archives/edgar/data/1322734/0001047469-11-002603.txt#7813 The citation records this snapshot. The page link may show a newer release later.

Capital expenditure uses the canonical mapped positive-spending convention. A missing, ambiguous, incompatible, or negative-sign input is left blank. Values use the latest reported version.

Dataset coverage and company identifiers

Coverage reflects filings processed into this Fundies dataset; it does not imply every source filing is loaded.

30 filings · 0 latest values · 0 originally reported values

Dataset published 2026-11-02. Source filing dates and reporting periods are shown separately.

Identifiers: 0001322734, 1322734, edgar:1322734

Advanced Life Sciences Holdings, Inc.

Latest quarter

Revenue

Operating margin

Operating cash flow

Free cash flow

Trailing twelve months

Revenue

Net income

Operating cash flow

Capital expenditure

Free cash flow

Company performance

What changed year over year

Revenue

Net income

Operating cash flow

Capital expenditure

Where revenue goes

2010 2010-01-01 – 2010-12-31

Cash

Share of revenue by period

Growth

Profit and cash

Balance sheet

Cash generation